CAS No.: | 755037-03-7 |
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Formula: | C21h15clf4n4o3 |
EINECS: | 815-051-1 |
Type: | Pharmaceutical Intermediates |
Appearance: | Powder |
Quality: | Refined |
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Customization: |
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Puya Supply API Regorafenib CAS 755037-03-7 Treatment Of Rectal Cancer
Product Name: Regorafenib
Synonyms: Regorafenib;BAY 73-4506;4-[4-({[4-Chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)-3-fluorophenoxy]-N-methylpyridine-2-carboxamide;BAY 73-4506(Regorafenib);4-(4-(3-(4-chloro-3-(trifluoroMethyl)phenyl)ureido)-3-fluorophenoxy)-N-MethylpicolinaMide;4-[4-({[4-chioro-3-(trifluoroMethyl)phenyl]carbaMoyl}aMino)-3-fluorophenoxy]-pyridine-2-carboxylic acid MethylaMide;REGORAFENIB BAY 73-4506 BAYER HEALTHCARE (SEE ALSO COLORECTAL, LUNG, STOMACH) PHASE II(REGORAFENIB) PHARMACEUTICALS (888) 842-2937WAYNE, NJ;Regorafenib (BAY 73-4506)
CAS: 755037-03-7
MF: C21H15ClF4N4O3
MW: 482.82
EINECS: 815-051-1
Product Categories: Inhibitors;API;Amines;Aromatics;Heterocycles;Anti-cancer&immunity;Intermediates & Fine Chemicals;Pharmaceuticals;API
Mol File: 755037-03-7.mol
Regifenib is an oral multi-kinase inhibitor that blocks multiple protein kinases associated with angiogenesis [VE GF receptors 1-3, tyrosine receptor kinase 2 (TIE2), the proto-oncogenes KIT, RET, RAF1, BRAF and BRAF V600E, the tumor microenvironment-related receptors platelet-derived grow th factor receptor (PDGFR) and fibroblast grow th factor receptor ( FGFR)]. Phase III studies have shown that regifenib improves overall survival (OS), progression-free survival (PFS) and disease control rate (DCR) in mCRC patients who have received multiple therapies, with a better safety profile and no reduction in quality of life (QoL).
Regorafenib CAS 755037-03-7 of Chemical PropertiesMelting point 206.0 to 210.0 °C
Boiling point 513.4±50.0 °C(Predicted)
density 1.491±0.06 g/cm3(Predicted)
storage temp. Refrigerator
solubility DMSO (Slightly), Methan ol (Slightly)
pka 12.04±0.70(Predicted)
form White powder.
color Pale Pink to Light Pink
CAS DataBase Reference 755037-03-7
Shipping Terms | ||
By Express | By Air | By Sea |
Suitable for under 50kg Fast:3-4 days High cost Door to door service Easy to pick up the goods |
Suitable for more than 50kg Fast:3-4 days High cost Airport to airport Professional broker needed |
Suitable for more than 500kg Slow:15-30 days Low cost Port to port Professional broker needed |
Company Profile
Anhui puya biological technology co.,ltd was established in Hefei. Registered capital is 5 million. It is specialized in manufacture plant extract, API and chemicals raw material powder, food additives and oil. which are applied to skin care, healthcare, weight loss products, sex improvement, and pharmaceuticals. We will uphold honesty and pragmatic, innovative and enterprising service purposes, and provide a variety of quality services to our customers at abroad. It aims at supplying good product and comfort service. The strict quality control is to meet the customer's requirement, to get a highly praised and to be high quality supplier. If you have any question, or need samples, please feel free to contact us.
FAQ
Q1. What's the MOQ?
A: Usually 1 kg. It is based on the different product. Some are 1g and some are 1 ton. Please be free to consult our salesman.
Q2. What's the shipping time?
A: If in stock, we will ship it out immediately. By FedEx will be 3~5 days to you.
Q3. If I need less than the MOQ, is it possible?
A: Yes. Please be free to consult our salesman.
Q4. Can you supply the free sample?
A: Usually it is possible. but the shipping cost be paid by customers. It based on the different product. Please be free to consult our salesman.
Q5. How to store the product?
A: Store in cool and dry place. It must be in well closed containers. The shelf life will be 2 years.
Q6: What's your main payment method?
A: T/T, trade assurance, west union, money gram.
Q7: Do you have COA, MSDS, CO, Health certificate, form 9 or other certificate?
A: Yes, we have. pls be free to contact us to get updated one.
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