CAS No.: | 22832-87-7 |
---|---|
Formula: | C18h15cl4n3o4 |
EINECS: | 245-256-6 |
Type: | Pharmaceutical Intermediates |
Appearance: | Powder |
Quality: | Refined |
Samples: |
---|
Customization: |
---|
Suppliers with verified business licenses
High Quality Miconazo le Nitrate CAS 22832-87-7 For Anti Fungus
Product Name: Miconazo le nitrate
Synonyms: Isoconazole IMpurity C Nitrate (Miconazo le Nitrate);1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole,nitrate (1:1);NSC 169434 Nitrate;1H-Imidazole, 1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-, nitrate (1:1);()-MICONAZO LE NITRATE SALT, IMIDAZO;1-(2,4-Dichloro-β-[(2,4-dichlorobenzyl)oxy]phenethyl)imidazole 1-[2-(2,4-Dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole Nitrate;monistat;MICONAZO LE NITRATE USP
CAS: 22832-87-7
MF: C18H15Cl4N3O4
MW: 479.14
EINECS: 245-256-6
Product Categories: MONISTAT;API;Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Active Pharmaceutical Ingredients;Organics;Antifungals for Research and Experimental Use;Biochemistry;API's;Antifungal;22832-87-7
Mol File: 22832-87-7.mol
Miconazo le nitrate is a kind of artificially synthetic 1-phenylethyl imidazole derivatives and belongs to imidazole-class broad-spectrum antifungal drug. It is a commonly used drug for treating skin ringworm without containing hormones and without side effects. Its main active ingredient is miconazo le. However, miconazo le nitrate is now seldom used in China. Its antibacterial spectrum, antibacterial activity and mechanism of action are all similar with clotrimazole. It can be used as a substitute drug when the treatment of amphotericin in deep fungal infection is invalid. It is suitable for treating the systemic, disseminated infection caused by some kinds of fungus such as Cryptococcus neoformans and Candida albicans. The efficacy of absorption via oral administration is poor. After topical administration, the drug is mainly maintained in the lesion place with only a small fraction getting absorbed into the body. In vivo, it is widely distributed in various body tissues and fluids and can penetrate into the inflamed joints, vitreous and the peritoneum, but the concentration in the sputum and saliva is low and it has a poor penetrating capability through the blood-brain barrier and is difficult to penetrate through the blood-brain barrier. It has a plasma protein binding rate of 90%. It is mainly inactive through liver metabolism into inactive metabolites with 14%~22% of the metabolites being excreted through urine, of which less than 1% of drug being in its prototype.
Miconazo le Nitrate CAS 22832-87-7 of Chemical Properties
Melting point 170-185 C
density 1.5000 (rough estimate)
refractive index 1.6200 (estimate)
storage temp. 2-8°C
solubility pyridi ne: soluble50mg/mL
form neat
color white to off-white
optical activity [α]25/D 0°, c = 10 in water
Water Solubility Slightly soluble in water. Soluble in propyle ne glycol or pyridi ne.
Merck 14,6178
InChIKey MCCACAIVAXEFAL-UHFFFAOYSA-N
CAS DataBase Reference 22832-87-7(CAS DataBase Reference)
Shipping Terms | ||
By Express | By Air | By Sea |
Suitable for under 50kg Fast:3-4 days High cost Door to door service Easy to pick up the goods |
Suitable for more than 50kg Fast:3-4 days High cost Airport to airport Professional broker needed |
Suitable for more than 500kg Slow:15-30 days Low cost Port to port Professional broker needed |
Company Profile
Anhui puya biological technology co.,ltd was established in Hefei. Registered capital is 5 million. It is specialized in manufacture plant extract, API and chemicals raw material powder, food additives and oil. which are applied to skin care, healthcare, weight loss products, sex improvement, and pharmaceuticals. We will uphold honesty and pragmatic, innovative and enterprising service purposes, and provide a variety of quality services to our customers at abroad. It aims at supplying good product and comfort service. The strict quality control is to meet the customer's requirement, to get a highly praised and to be high quality supplier. If you have any question, or need samples, please feel free to contact us.
FAQ
Q1. What's the MOQ?
A: Usually 1 kg. It is based on the different product. Some are 1g and some are 1 ton. Please be free to consult our salesman.
Q2. What's the shipping time?
A: If in stock, we will ship it out immediately. By FedEx will be 3~5 days to you.
Q3. If I need less than the MOQ, is it possible?
A: Yes. Please be free to consult our salesman.
Q4. Can you supply the free sample?
A: Usually it is possible. but the shipping cost be paid by customers. It based on the different product. Please be free to consult our salesman.
Q5. How to store the product?
A: Store in cool and dry place. It must be in well closed containers. The shelf life will be 2 years.
Q6: What's your main payment method?
A: T/T, trade assurance, west union, money gram.
Q7: Do you have COA, MSDS, CO, Health certificate, form 9 or other certificate?
A: Yes, we have. pls be free to contact us to get updated one.
Suppliers with verified business licenses