| CAS No.: | 1029712-80-8 |
|---|---|
| Formula: | C23h17fn6o |
| EINECS: | 813-241-9 |
| Type: | Pharmaceutical Intermediates |
| Appearance: | Powder |
| Quality: | Refined |
| Customization: |
|---|
Suppliers with verified business licenses
Audited Supplier Puya Supply Capmatinib CAS 1029712-80-8 For Anti Tumor
Product Name: Capmatinib
Synonyms: INCB028060;CapMatinib (INCB28060);CapMatinib;NC280 BenzaMide,2-fluoro-N-Methyl-4-[7-(6-quinolinylMethyl)iMidazo[1,2-b][1,2,4]triazin-2-yl]-;NVP-INC280;2-Fluoro-N-methyl-4-[7-[(quinolin-6-yl)methyl]imidazo[1,2-b]-[1,2,4]triazin-2-yl]benzamide Capmatinib (INCB28060);INCB28060, INC280;INC28060
CAS: 1029712-80-8
MF: C23H17FN6O
MW: 412.42
EINECS: 813-241-9
Product Categories: Inhibitors;API
Mol File: 1029712-80-8.mol
Capmatinib(Synonyms: INC280; INCB28060) is a competitive inhibitor with very potent and selective activity against MET compared to other kinases. It has been shown in vitro that cell lines made resistant to erlotinib, an EGFR inhibitor, could be resensitized after capmatinib treatment. Results from a phase Ib/II study of patients with EGFR-mutated, MET-dysregulated NSCLC have shown promising responses to a combination of capmatinib and gefiti nib (EGFR TKI) following disease progression from an only EGFR TKI treatment regimen. Recommended phase II dose was determined to be capmatinib 400 mg twice/day and gefiti nib 250 mg once/day. Most common adverse events were nausea, peripheral edema, decreased appetite, rash, and increased amylase and lipase levels.
Capmatinib CAS 1029712-80-8 of Chemical Properties
Melting point >250°C (dec.)
density 1.40
vapor pressure 0-0Pa at 20-25ºC
storage temp. -20°C Freezer, Under inert atmosphere
solubility DMSO (Slightly), Methan ol (Slightly)
pka 13.82±0.46(Predicted)
form Solid
color Pale Yellow to Light Yellow
LogP 1.6-2.2 at 35ºC and pH7-9
| Shipping Terms | ||
| By Express | By Air | By Sea |
| Suitable for under 50kg Fast:3-4 days High cost Door to door service Easy to pick up the goods |
Suitable for more than 50kg Fast:3-4 days High cost Airport to airport Professional broker needed |
Suitable for more than 500kg Slow:15-30 days Low cost Port to port Professional broker needed |
Company Profile
Anhui puya biological technology co.,ltd was established in Hefei. Registered capital is 5 million. It is specialized in manufacture plant extract, API and chemicals raw material powder, food additives and oil. which are applied to skin care, healthcare, weight loss products, sex improvement, and pharmaceuticals. We will uphold honesty and pragmatic, innovative and enterprising service purposes, and provide a variety of quality services to our customers at abroad. It aims at supplying good product and comfort service. The strict quality control is to meet the customer's requirement, to get a highly praised and to be high quality supplier. If you have any question, or need samples, please feel free to contact us.
FAQ
Q1. What's the MOQ?
A: Usually 1 kg. It is based on the different product. Some are 1g and some are 1 ton. Please be free to consult our salesman.
Q2. What's the shipping time?
A: If in stock, we will ship it out immediately. By FedEx will be 3~5 days to you.
Q3. If I need less than the MOQ, is it possible?
A: Yes. Please be free to consult our salesman.
Q4. Can you supply the free sample?
A: Usually it is possible. but the shipping cost be paid by customers. It based on the different product. Please be free to consult our salesman.
Q5. How to store the product?
A: Store in cool and dry place. It must be in well closed containers. The shelf life will be 2 years.
Q6: What's your main payment method?
A: T/T, trade assurance, west union, money gram.
Q7: Do you have COA, MSDS, CO, Health certificate, form 9 or other certificate?
A: Yes, we have. pls be free to contact us to get updated one.
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