High Quality Carfilzomib CAS 868540-17-4 Treatment of Bone Marrow Tumour

• CAS No.: 868540-17-4
• Formula: C40h57n5o7
• EINECS: 692-054-2
• Type: Pharmaceutical Intermediates
• Appearance: Powder
• Quality: Refined
• Model NO.: PY202211051442
• Colour: White
• Transport Package: 1kg/Aluminum Bag or 25kg/Drum
• Specification: 99% min
• Trademark: Puya
• Origin: China
• Production Capacity: 5000kilogram/Month

Product Description

High Quality Carfilzomib CAS 868540-17-4 Treatment Of Bone Marrow Tumour
Product Name:    Carfilzomib
Synonyms:    N-{(2S)-2-[(Morpholin-4-ylacetyl)aMino]-4-phenylbutanoyl}-L-leucyl-N-{(2S)-4-Methyl-1-[(2R)-2-Methyloxiran-2-yl]-1-oxopentan-2-yl}-L-phenylalaninaMide;CarfilzoMib salt;CarfilzoMib/PR 171;PR 171;PR-171 (CarfilzoMib);(alphaS)-alpha-[(4-Morpholinylacetyl)amino]benzenebutanoyl-L-leucyl-N-[(1S)-3-methyl-1-[[(2R)-2-methyloxiranyl]carbonyl]butyl]-L-phenylalaninamide;Carfilzomib;Carfilzomib API and intermediates
CAS:    868540-17-4
MF:    C40H57N5O7
MW:    719.92
EINECS:    692-054-2
Product Categories:    Inhibitors;peptides;Inhibitor;API;Pharmaceutical
Mol File:    868540-17-4.mol


Carfilzomib is an irreversible proteasome inhibitor and antineoplastic agent.The mechanism of action of carfilzomib is as a Proteasome Inhibitor, Carfilzomib irreversibly binds to and inhibits the chymotrypsin-like activity of the 20S catalytic core subunit of the proteasome, a protease complex responsible for degrading a large variety of cellular proteins. Inhibition of proteasome-mediated proteolysis results in an accumulation of polyubiquinated proteins, which may lead to cell cycle arrest, induction of apoptosis, and inhibition of tumor growth.
Carfilzomib is used in treatment of refractory multiple myeloma. Carfilzomib is associated with a low rate of serum enzyme elevations during treatment and has been implicated to rare instances of clinically apparent, acute liver injury some of which have been fatal.

Carfilzomib CAS 868540-17-4 of Chemical Properties
Melting point     204 - 208°C
Boiling point     975.6±65.0 °C(Predicted)
density     1.161
Fp     543.8ºC
storage temp.     -20°
solubility     Soluble in DMSO (up to 80 mg/ml) or in Ethanol (up to 25 mg/ml).
form     solid
pka    13.17±0.46(Predicted)
color     White
Stability:    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 week.
CAS DataBase Reference    868540-17-4

Function and Application of Carfilzomib CAS 868540-17-4
Carfilzomib (CAS 868540-17-4) is a medication used in the treatment of multiple myeloma, a type of blood cancer that affects the plasma cells in the bone marrow. Carfilzomib belongs to a class of drugs called proteasome inhibitors, which work by blocking the activity of proteasomes, structures within cells that break down proteins. This leads to the accumulation of abnormal proteins within the cancer cells, which can ultimately lead to their death.

Function:
The primary function of carfilzomib is to inhibit the activity of proteasomes, which are responsible for breaking down proteins within cells. By blocking the proteasomes, carfilzomib prevents the degradation of certain proteins that are essential for the survival and growth of cancer cells. This ultimately leads to the death of the cancer cells.

Application:
Carfilzomib is mainly used in the treatment of multiple myeloma, which is a type of blood cancer that affects the plasma cells in the bone marrow. It is often used in combination with other medications, such as dexamethaso ne, to help improve the overall effectiveness of the treatment. Carfilzomib may also be used in the treatment of other types of cancer, such as lymphoma and solid tumors, although this is less common.



Packing And Shipping
1.Preferentially DHL, FedEX or TNT for quantity less than 50kg, air shipping for 100kg above, sea shipping for quantity over 500kg.
2.For customers from Russia,Mexico,Turkey,Solvenia,Romania,etc,before placing an order,please kindly confirm if you can make clearance when goods reach your customs.

Shipping Terms
By Express	By Air	By Sea
Suitable for under 50kg Fast:3-4 days High cost Door to door service Easy to pick up the goods	Suitable for more than 50kg Fast:3-4 days High cost Airport to airport Professional broker needed	Suitable for more than 500kg Slow:15-30 days Low cost Port to port Professional broker needed

 

Company Profile
Anhui puya biological technology co.,ltd was established in Hefei. Registered capital is 5 million. It is specialized in manufacture plant extract, API and chemicals raw material powder, food additives and oil. which are applied to skin care, healthcare, weight loss products, sex improvement, and pharmaceuticals. We will uphold honesty and pragmatic, innovative and enterprising service purposes, and provide a variety of quality services to our customers at abroad. It aims at supplying good product and comfort service. The strict quality control is to meet the customer's requirement, to get a highly praised and to be high quality supplier. If you have any question, or need samples, please feel free to contact us.

FAQ
Q1. What's the MOQ?
A: Usually 1 kg.  It is based on the different product. Some are 1g and some are 1 ton. Please be free to consult our salesman.
 
Q2. What's the shipping time?
A: If in stock, we will ship it out immediately.  By FedEx will be 3~5 days to you.
 
Q3. If I need less than the MOQ, is it possible?
A: Yes. Please be free to consult our salesman.
 
Q4. Can you supply the free sample?
A: Usually it is possible. but the shipping cost be paid by customers. It based on the different product. Please be free to consult our salesman.
 
Q5. How to store the product?
A: Store in cool and dry place. It must be in well closed containers. The shelf life will be 2 years.
 
Q6: What's your main payment method?
A: T/T, trade assurance, west union, money gram.
 
Q7: Do you have COA, MSDS, CO, Health certificate, form 9 or other certificate?
A: Yes, we have. pls be free to contact us to get updated one.