Puya Supply Diquafosol Sodium CAS 211427-08-6 Treatment of Dry Eye Disease

• CAS No.: 211427-08-6
• Formula: C18h27n4nao23p4
• EINECS: 253-874-2
• Type: Pharmaceutical Intermediates
• Appearance: Powder
• Quality: Refined
• Model NO.: PY202303021701
• Colour: White
• Transport Package: 1gram/Bag
• Specification: 99% min
• Trademark: Puya
• Origin: China
• Production Capacity: 5kilogram/Month

Product Description

 Puya Supply Diquafosol Sodium CAS 211427-08-6 Treatment Of Dry Eye Disease

Product Name:    INS 365
Synonyms:    INS 365;D03864;Diquafosol sodium;Diquafosol sodium (jan);Diquafosol tetrasodium;Diquafosol tetrasodium (usan);Diquafosol Impurity 7(UP4U);[[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl] [[[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl]oxy-oxidophosphoryl] phosphate
CAS:    211427-08-6
MF:    C18H27N4NaO23P4
MW:    814.3
EINECS:    253-874-2
Product Categories:    
Mol File:    211427-08-6.mol

Diquafosol (INS-365) was approved in Japan in 2010 as a 3% ophthalmic solution for treatment of dry eye disease. Clinical diagnosis of dry eye is difficult because the condition presents a variety of symptoms. Treatment options include tear supplements (lubricants), anti-inflammatory drugs (e.g., cyclosporine eye drops or steroid eye drops), and tear retention devices. Diquafosol is a unique agent for the treatment of dry eye in that it acts as a P2Y2 purinergic receptor agonist with the ability to activate this receptor on the ocular surface and stimulate water, lipid, and mucin secretion. Diquafosol is metabolized by phosphodiesterases to UTP, UDP, UMP, and uridine. Diquafosol has been well tolerated in clinical trials, with side effects being local to the ocular surface.In addition,no serious ocular or systemic adverse drug reactions were found during the clinical trials.

Diquafosol Sodium CAS 211427-08-6 of Chemical PropertiesSolubility: Diquafosol sodium is soluble in water, with a solubility of approximately 70 mg/mL at 25°C.
Stability: The compound is stable under normal storage conditions but should be protected from light and moisture.
pH: Diquafosol sodium has a pH of approximately 5.5.
Ionization: Diquafosol sodium is a salt that ionizes in solution, releasing a sodium ion (Na+) and a negatively charged diquafosol molecule.
Hygroscopicity: Diquafosol sodium is hygroscopic, meaning it can absorb moisture from the air.

Function and Application of Diquafosol Sodium CAS 211427-08-6
Diquafosol sodium (CAS 211427-08-6) is a medication used to treat dry eye syndrome, a condition that occurs when the eyes are unable to produce enough tears to keep them moist and lubricated.

The function of diquafosol sodium is to stimulate the production of tears by activating the P2Y2 receptor in the ocular surface, which promotes the secretion of water and electrolytes in the tear film. This results in an increase in tear volume and improvement in the signs and symptoms of dry eye syndrome.


Packing And Shipping
1.Preferentially DHL, FedEX or TNT for quantity less than 50kg, air shipping for 100kg above, sea shipping for quantity over 500kg.
2.For customers from Russia,Mexico,Turkey,Solvenia,Romania,etc,before placing an order,please kindly confirm if you can make clearance when goods reach your customs.

Shipping Terms
By Express	By Air	By Sea
Suitable for under 50kg Fast:3-4 days High cost Door to door service Easy to pick up the goods	Suitable for more than 50kg Fast:3-4 days High cost Airport to airport Professional broker needed	Suitable for more than 500kg Slow:15-30 days Low cost Port to port Professional broker needed

 

Company Profile
Anhui puya biological technology co.,ltd was established in Hefei. Registered capital is 5 million. It is specialized in manufacture plant extract, API and chemicals raw material powder, food additives and oil. which are applied to skin care, healthcare, weight loss products, sex improvement, and pharmaceuticals. We will uphold honesty and pragmatic, innovative and enterprising service purposes, and provide a variety of quality services to our customers at abroad. It aims at supplying good product and comfort service. The strict quality control is to meet the customer's requirement, to get a highly praised and to be high quality supplier. If you have any question, or need samples, please feel free to contact us.

FAQ
Q1. What's the MOQ?
A: Usually 1 kg.  It is based on the different product. Some are 1g and some are 1 ton. Please be free to consult our salesman.
 
Q2. What's the shipping time?
A: If in stock, we will ship it out immediately.  By FedEx will be 3~5 days to you.
 
Q3. If I need less than the MOQ, is it possible?
A: Yes. Please be free to consult our salesman.
 
Q4. Can you supply the free sample?
A: Usually it is possible. but the shipping cost be paid by customers. It based on the different product. Please be free to consult our salesman.
 
Q5. How to store the product?
A: Store in cool and dry place. It must be in well closed containers. The shelf life will be 2 years.
 
Q6: What's your main payment method?
A: T/T, trade assurance, west union, money gram.
 
Q7: Do you have COA, MSDS, CO, Health certificate, form 9 or other certificate?
A: Yes, we have. pls be free to contact us to get updated one.