Pharmaceutical Raw Material Metronidazole CAS 443-48-1

• Function: Vitamins and Minerals Deficiency Drug
• Certification: GMP
• Grade Standard: Medicine Grade
• Type: Chemical Reagent
• State: Powder
• Volatile: Not Volatile
• Model NO.: py0443
• CAS: 443-48-1
• Mf.: C6h9n3o3
• Standard: USP Bp Ep
• MOQ: 1kg
• Transport Package: 25kg/Drum
• Specification: 99%
• Trademark: puya
• Origin: China
• Production Capacity: 50ton/Year

Product Description

Metronidazole CAS 443-48-1

Product Name	Metronidazole
CAS	443-48-1
MF	C18H14F3N3O4S
MW	171.156 g/mol
storage temp.	2-8°C
Appearance	White powder
Assay	98%min

Metronidazole is an antibiotic that is used commonly to treat protozoal infections and anaerobic bacterial infections. It also has anti-inflammatory effects in the bowel. Metronidazole is bactericidal; it kills bacterial microorganisms by disrupting their DNA. It is absorbed rapidly from the GI tract, metabolized by the liver and excreted in the urine and the feces. Because metronidazole only has activity against anaerobic bacteria, it is used commonly with other antibiotics when it is used to treat mixed-bacterial infections. It is compatible with many other antibiotics including penicillin antibiotics, aminoglycosides, and some cephalosporins.

Application

1. Metronidazole has the function of  broad spectrum of anaerobic bacteria and peptides.
2. Metronizalole is mainly used for the prevention and treatment of infections caused by anaerobic bacteria, like respiratory tract; digestive tract; the infection of enterocoelia and pelvic cavity; skin and soft tissue; bone and joint infection; endocarditis, brain abscess, blood poisoning and meningitis caused by bacteroides fragilis.
3. Metronizalole is widely used in the prevention and treatment of oral anaerobic bacteria infection.
4. Metronidazole has strong antibacterial effect to most anaerobic bacteria, used in the treatment of amebiasis, trichomoniasis and anaerobic infections.

Function
1. Anti-Vaginal Trichomonas.
Metronidazole is currently the world's specific medicine for the treatment of trichomonas vaginitis, oral administration of 10mg/kg can treat Trichomonas vaginalis, but it will not affect the growth of normal vaginal flora. Anti-amebic infection. Metronidazole can be used to treat amoebiasis both inside and outside the intestine, and it is the first choice for anti-amoebic infections.
2. Prevent infection after surgery.
The preventive use of metronidazole before and after surgery can significantly reduce the infection rate of the wound. It is mainly used for anti-infection of appendectomy, rectal and colon surgery, abdominal infection, etc.
3. Treatment of peptic ulcer.
Metronidazole can protect mucosa and promote mucosal regeneration. For gastric and duodenal ulcers, use metronidazole 1g/day in 3 doses to achieve the ideal cure rate and ulcer healing rate.
4. Treatment of chronic cough with abscess caused by bronchopneumonia infection.
Metronidazole can quickly control infection and improve symptoms.
5. Hyperlipidemia.
Metronidazole has a significant effect on lowering blood lipids. It is taken 3 times a day, 0.2-0.4g each time, for 4 weeks.
6. Treat tetanus.
There are literatures that metronidazole has a very good therapeutic effect on tetanus, even higher than penicillin. While applying metronidazole, debride the wound, inject antitoxin and intravenous fluid. Admit that 1.6-2.6g per day, divided into 3-4 times orally; children take 50mg per kilogram per day for 1-2 courses of treatment.
7. Oral diseases.
Periodontitis, gingivitis, periodontal abscess, upper frontal sinusitis, tonsillitis, etc. The usage is 3 times a day, 0.2-0.8g each time, taking one week continuously as a course of treatment