| CAS No.: | 23110-15-8 |
|---|---|
| Formula: | C26h34o7 |
| EINECS: | 245-433-8 |
| Type: | Pharmaceutical Intermediates |
| Appearance: | Powder |
| Quality: | Refined |
| Samples: |
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| Customization: |
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Audited Supplier Puya Supply Fumagillin CAS 23110-15-8 With Good Price
Product Name: FUMAGILLIN
Synonyms: 1-oxaspiro(2,5)oct-6-ylester;2,4,6,8-decatetraenedioicacid,mono[5-methoxy-4-[2-methyl-3-(3-methyl-2-buteny;5beta,6beta(all-e)]]-theta;6,8-decatetraenedioicacid,4-(1,2-epoxy-1,5-dimethyl-4-hexenyl)-5-methoxy-4;amebacillin;10-[[5-Methoxy-4-[2-methyl-3-(3-methylbut-2-enyl)oxiran-2-yl]-2-oxaspiro[2.5]oct-6-yl]oxy]-10-oxo-deca-2,4,6,8-tetraenoic acid;Fumagilin DCH;[3R-[3alpha,4alpha(2RX,3RX),5beta,6beta(all-E)]]-2,4,6,8-Decatetraenedioic acid, mono[5-methoxy-4-[2-methyl-3-(3-methyl-2-butenyl)oxiranyl]-1-oxaspiro[2.5]oct-6-yl] ester
CAS: 23110-15-8
MF: C26H34O7
MW: 458.54
EINECS: 245-433-8
Product Categories: Peptide Synthesis/Antibiotics;API
Mol File: 23110-15-8.mol
Fumagillin is an antibiotic derived from the fungus Aspergillus fumigatus. It has widely been used both in human and veterinary medicine. It has appeared to be the most effective medicine in supressing cryptosporidiosis and microsporidiosis caused by Enterocytozoon bieneusi which can be fatal in HIV-infected persons[1, 2]. Due to its antiparasitic efficacy fumagillin has also been widely applied in veterinary medicine against microsporidiosis of bees and fish[3-5]. Fumagillin is very stable in honey[6] even at higher temperatures; for example it was detectable after having been kept at 80oC for 35 days[7]. Mixed with syrup it is very effective in supressing Nosema in hibernating honeybee colonies. However, it has not been effective against dormant spores of Nosema apis, thus has never eliminated the disease in the bee colony entirely.
Fumagillin has also been used in the treatment of microsporidiosis in fish including the ones caused by Myxobolus cerebralis[4,8] and Tetracapsuloides bryosalmona[9-11]. It is effective in curing microsporidial keratoconjunctivitis[12, 13]. Taken in orally it has appeared highly effective against chronic Enterocytozoon bieneusi infections in patients with AIDS and other types of immunodeficiencies[14]. For further administration, however, appropriate therapeutical models should be completely improved and side effects of the treatment should be eliminated[15].
Fumagillin CAS 23110-15-8 of Chemical Properties
Melting point 194-195ºC
alpha D25 -26.6° (c = 1 in 95% ethanol)
Boiling point 484.03°C (rough estimate)
density 1.1368 (rough estimate)
refractive index 1.5800 (estimate)
Fp 2ºC
storage temp. 2-8°C
solubility ethanol: 1 mg/mL
form powder
pka 4.27±0.10(Predicted)
color white
Sensitive Air Sensitive
Stability: Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
InChIKey NGGMYCMLYOUNGM-ZILXAVPASA-N
Function and Application of Fumagillin CAS 23110-15-8
| Shipping Terms | ||
| By Express | By Air | By Sea |
| Suitable for under 50kg Fast:3-4 days High cost Door to door service Easy to pick up the goods |
Suitable for more than 50kg Fast:3-4 days High cost Airport to airport Professional broker needed |
Suitable for more than 500kg Slow:15-30 days Low cost Port to port Professional broker needed |
Company Profile
Anhui puya biological technology co.,ltd was established in Hefei. Registered capital is 5 million. It is specialized in manufacture plant extract, API and chemicals raw material powder, food additives and oil. which are applied to skin care, healthcare, weight loss products, sex improvement, and pharmaceuticals. We will uphold honesty and pragmatic, innovative and enterprising service purposes, and provide a variety of quality services to our customers at abroad. It aims at supplying good product and comfort service. The strict quality control is to meet the customer's requirement, to get a highly praised and to be high quality supplier. If you have any question, or need samples, please feel free to contact us.
FAQ
Q1. What's the MOQ?
A: Usually 1 kg. It is based on the different product. Some are 1g and some are 1 ton. Please be free to consult our salesman.
Q2. What's the shipping time?
A: If in stock, we will ship it out immediately. By FedEx will be 3~5 days to you.
Q3. If I need less than the MOQ, is it possible?
A: Yes. Please be free to consult our salesman.
Q4. Can you supply the free sample?
A: Usually it is possible. but the shipping cost be paid by customers. It based on the different product. Please be free to consult our salesman.
Q5. How to store the product?
A: Store in cool and dry place. It must be in well closed containers. The shelf life will be 2 years.
Q6: What's your main payment method?
A: T/T, trade assurance, west union, money gram.
Q7: Do you have COA, MSDS, CO, Health certificate, form 9 or other certificate?
A: Yes, we have. pls be free to contact us to get updated one.
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