5-Ala/5-Aminolevulinic Acid HCl CAS 5451-09-2

• Function: Vitamins and Minerals Deficiency Drug
• Grade Standard: Food Grade
• Type: Chemical Reagent
• State: Powder
• Volatile: Not Volatile
• CAS: 5451-09-2
• Model NO.: py0518
• Mf,: C5h10clno3
• MOQ: 1kg
• Package: Carton
• Transport Package: 1kg/Bag, 25kg/Drum
• Specification: 99%
• Trademark: puya
• Origin: China
• Production Capacity: 5000kg/Year

Product Description

5-ALA/5-Aminolevulinic Acid HCl CAS 5451-09-2

[English name]: 5-Aminolevulinic acid hydrochloride
[CAS number]: 5451-09-2
[Molecular formula]: C5H9NO3·HCl
[Molecular weight]: 167.59
[chemical name]: 5-aminolevulinic acid hydrochloride
[product nickname]: 5-aminolevose hydrochloride; Β-aminolevulinic acid hydrochloride; 5-amino-fructose hydrochloride; 5-aminolevulinic acid hydrochloride; 5-aminolevose; 5-aminolevulinic acid; DELTA-aminolevulinic acid hydrochloride; aminolevulinic acid; 5-aminoacetic acid hydrochloride
[Main components]: 5-ALA
[Appearance]: White crystal powder
[Physical properties]: It is hygroscopic. Sensitive to light. Soluble in water and ethanol, very slightly soluble in ethyl acetat. The temperature of 144 ~ 147 ° C (decomposition). The maximum absorption wavelength (in water) is 266.5 nm (ε 23.0). Irritating.
[source of raw materials]: synthesis
[Application direction]: raw materials
[Supply specifications]: 95%,99%; 
[Test method]: HPLC
[Storage method]: Store in a cool dry place, avoiding light and avoiding high temperature.

Function
5-aminolevulinic acid (5-ALA), molecular formula C5H9N03, melting point 149-151 ° C. 5-ALA is a prefix compound of substance constituting heme, cytochrome, and vitamin B12), and is an essential substance for biosynthesis of chlorophyll, heme, and vitamin B12.
1. 5-ALA is a new type of photoactivated pesticide with high environmental compatibility and high selectivity. It is widely used in agriculture.
(1) Plant growth regulators Recent studies have shown that 5-ALA has the following effects: regulating chlorophyll synthesis; improving the stability of chlorophyll and light-harvesting system II; improving photosynthesis efficiency to promote photosynthesis; promoting plant tissue differentiation and inhibition Basic physiological activity such as breathing in the dark and expanding stomata. Therefore, it is not simply a biological metabolic intermediate, but also involved in the regulation of plant growth and development. It has physiological activity similar to phytohormone and can be used as a plant growth regulator in agricultural production.
(2) Green herbicides Herbicides produced by 5-ALA can kill weeds of dicotyledonous plants, but are harmless to crops such as grains, wheat, barley, etc., which are mostly monocotyledonous plants, and have selective herbicidal action. There are two principles of action: the first gene that inhibits GluTR and prevents the synthesis of 5-ALA, so that the plant eventually dies due to the lack of 5-ALA. 5-ALA synthesis in mammals does not pass through the C5 pathway, so the use of such herbicides does not adversely affect the human body. The second can relieve the regulation mechanism of 5-ALA synthesis and promote the synthesis of 5-ALA. For example, acifluorferr methyl can inhibit the synthesis of heme in plants, so that 5-ALA and porphyrin compounds accumulate in large quantities, which induces peroxidation under illumination. . However, since the market price of 5-ALA is relatively high, and it is required to use a higher mass concentration as a herbicide, the cost is large, and it is difficult to directly apply it at a time.
(3) Insecticides can cause imbalance of in vivo biochemical metabolism of various pests such as housefly, cockroach, etc., thereby causing cockroaches and even death of pests, and research on porphyrin insecticides using 5-ALA as a main component. In the source area of the Chinese rice borer, all the males in the treatment group died within 7 days, while the number of male deaths in the control group was about half, and the number of female deaths did not differ significantly at low concentrations. The principle is: 5-ALA activation can produce reactive oxygen species, and the insects can be converted into radioactive insecticides by plant photosynthesis or by triggering the cytochemical synthesis of pests. This study shows that it is a non-polluting natural substance that is biodegradable without causing pest resistance. A new type of green insecticide can be developed.
2, medically, 5-ALA as a new type of photodynamic drug, not only for the treatment of local or systemic skin cancer, but also for the diagnosis of bladder cancer, digestive tract cancer, lung cancer, etc.
3, 5-ALA is also an important organic synthesis intermediate. Because of its extensive and safe effect, and its natural pollution-free, it has attracted the attention of scholars and industry at home and abroad, and has broad application prospects and market development prospects.

Specification

ANALYSIS	SPECIFICATION	RESULTS
Appearance	Almost white powder	Almost white powder
Identification	FT-IR, HPLC, NMR, Mass	Complies
Assay	98.0%-102.0%	99.86%
Loss on drying	≤1.0%	0.71%
Residue on ignition	≤0.5%	0.15%
Melting point	149°C --160°C	156.3°C --158.5°C
Heavy metals	≤20ppm	Complies
Iron	≤20ppm	Complies
Bacteria endotoxins	≤0.4 USP EU/mg	0.2 EU/mg
Impurities
Any other single impurity	≤0.3%	Complies
Total impurities	≤1.0%	0.08%
Microbial Limits
Total aerobic microbial count	≤100 cfu/g	Confirm
Staphylococcus aureus	Absence	Absence
Pseudomonas aeruginosa	Absence	Absence
Salmonella species	Absence	Absence
Escherichia Coli	Absence	Absence