Hot Sale Mevastatin CAS 73573-88-3 with Safe Delivery

• CAS No.: 73573-88-3
• Formula: C23h34o5
• EINECS: 700-442-0
• Type: Pharmaceutical Intermediates
• Appearance: Powder
• Quality: Refined
• Model NO.: PY202211011318
• Colour: White
• Transport Package: 1kg/Aluminum Bag or 25kg/Drum
• Specification: 99% min
• Trademark: Puya
• Origin: China
• Production Capacity: 5000kilogram/Month

Product Description

Hot Sale Mevastatin CAS 73573-88-3 With Safe Delivery

Product Name:    Mevastatin
Synonyms:    Butanoic acid, 2-methyl-, (1S,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-7-methyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl ester, (2S)-;ML-236B;,8-beta(2s*,4s*),8a-beta))-;antibioticml236b;butanoicacid,2-methyl-,1,2,3,7,8,8a-hexahydro-7-methyl-8-(2-(tetrahydro-4-hy;compactin(penicillium);(S)-2-Methylbutyric acid [(1S,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-7-methyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]naphthalen-1-yl] ester;2-Methyl-butanoic acid [1S-[1-α(R*),7-β,8-β(2S*,4S*),8a-β]]-1,2,3,7,8,8a-hexahydro-7-methyl-8-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl]-1-naphthalenyl ester
CAS:    73573-88-3
MF:    C23H34O5
MW:    390.51
EINECS:    700-442-0
Product Categories:    Intermediates & Fine Chemicals;Metabolites & Impurities;Various Metabolites and Impurities;Metabolites;Cardiovascular APIs;Inhibitors;Active Pharmaceutical Ingredients;Pharmaceuticals;HMG-CoA reductase
Mol File:    73573-88-3.mol
 

Mevastatin, also known as Compactin, is a naturally occurring statin that was first isolated from the fungus Penicillium citrinum. Its chemical formula is C23H34O5 and its CAS number is 73573-88-3.

Mevastatin is a potent inhibitor of HMG-CoA reductase, an enzyme that is involved in cholesterol biosynthesis. By inhibiting this enzyme, mevastatin reduces the amount of cholesterol produced in the body, which can help to lower blood cholesterol levels.

Mevastatin was one of the first statins to be developed and was initially used as a cholesterol-lowering drug. However, it was withdrawn from the market due to its toxicity and was replaced by other statins such as lovastatin and simvastatin.

Mevastatin CAS 73573-88-3 of Chemical Properties
Melting point     151-153 °C
alpha     D22 +283° (c = 0.48 in aceto ne)
Boiling point     555.0±50.0 °C(Predicted)
density     1.13±0.1 g/cm3(Predicted)
vapor pressure     0Pa at 25ºC
storage temp.     2-8°C
solubility     DMSO: 20 mg/mL
form     powder
pka    13.49±0.40(Predicted)
color     white
λmax    246nm(MeOH)(lit.)
Merck     14,6164
BRN     1269441
InChIKey    AJLFOPYRIVGYMJ-INTXDZFKSA-N
CAS DataBase Reference    73573-88-3(CAS DataBase Reference)

Function and Application of Mevastatin CAS 73573-88-3
1. A fungal metabolite which is a potent inhibitor of HMG-CoA reductase.
2. antihyperlipidemic, HMGCoA reductase inhibitor
3. Mevastatin (compactin) is a diterpene produced by several species of the genera Penicillium and Monascus, first reported in 1976. Mevastatin, the prtotype of the statin class, is a potent competitive inhibitor of HMG-CoA reductase, a regulatory enzyme for cholesterol biosynthesis. Mevastatin has also been shown to induce apoptosis by inhibiting post-translational prenylation of proteins such as Ras, increasing eNOS mRNA and protein levels by blocking the geranylgeranylation of Rho, and inhibiting myoblast fusion. It induces cell cycle arrest in late G1 phase and may induce bone morphogenic protein-2 (BMP-2).
4. anti-hyperlipoproteinemic, 3-hydroxy-3-methyl glutaryl coenzyme A (HMG-CoA) reductase inhibitor


Packing And Shipping
1.Preferentially DHL, FedEX or TNT for quantity less than 50kg, air shipping for 100kg above, sea shipping for quantity over 500kg.
2.For customers from Russia,Mexico,Turkey,Solvenia,Romania,etc,before placing an order,please kindly confirm if you can make clearance when goods reach your customs.

Shipping Terms
By Express	By Air	By Sea
Suitable for under 50kg Fast:3-4 days High cost Door to door service Easy to pick up the goods	Suitable for more than 50kg Fast:3-4 days High cost Airport to airport Professional broker needed	Suitable for more than 500kg Slow:15-30 days Low cost Port to port Professional broker needed

 

Company Profile
Anhui puya biological technology co.,ltd was established in Hefei. Registered capital is 5 million. It is specialized in manufacture plant extract, API and chemicals raw material powder, food additives and oil. which are applied to skin care, healthcare, weight loss products, sex improvement, and pharmaceuticals. We will uphold honesty and pragmatic, innovative and enterprising service purposes, and provide a variety of quality services to our customers at abroad. It aims at supplying good product and comfort service. The strict quality control is to meet the customer's requirement, to get a highly praised and to be high quality supplier. If you have any question, or need samples, please feel free to contact us.

FAQ
Q1. What's the MOQ?
A: Usually 1 kg.  It is based on the different product. Some are 1g and some are 1 ton. Please be free to consult our salesman.
 
Q2. What's the shipping time?
A: If in stock, we will ship it out immediately.  By FedEx will be 3~5 days to you.
 
Q3. If I need less than the MOQ, is it possible?
A: Yes. Please be free to consult our salesman.
 
Q4. Can you supply the free sample?
A: Usually it is possible. but the shipping cost be paid by customers. It based on the different product. Please be free to consult our salesman.
 
Q5. How to store the product?
A: Store in cool and dry place. It must be in well closed containers. The shelf life will be 2 years.
 
Q6: What's your main payment method?
A: T/T, trade assurance, west union, money gram.
 
Q7: Do you have COA, MSDS, CO, Health certificate, form 9 or other certificate?
A: Yes, we have. pls be free to contact us to get updated one.