CAS No.: | 53-86-1 |
---|---|
Formula: | C19h16clno4 |
EINECS: | 200-186-5 |
Type: | Pharmaceutical Intermediates |
Appearance: | Powder |
Quality: | Refined |
Samples: |
---|
Customization: |
---|
Suppliers with verified business licenses
Hot Sale Indometacin CAS 53-86-1 For Anti-inflammatory
Product Name: Indometacin
Synonyms: 1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-ylacetic acid;indomethacin crystalline;indomethacin metha nol solution;indomethacin usp;AURORA KA-6542;INDOCIN;INDOMETACIN;INDOMETACINE
CAS: 53-86-1
MF: C19H16ClNO4
MW: 357.79
EINECS: 200-186-5
Product Categories: Active Pharmaceutical Ingredients;PHARMACEUTICALS;Lipid signaling;INDOCIN;Other APIs;Pharmaceutical raw chemicals;All Inhibitors;Inhibitors;Intermediates & Fine Chemicals
Mol File: 53-86-1.mol
Indomethacin, chemically known as 2-methyl-1-(4-chlorobenzoyl)-5-methoxy-1H-indole-3-acetic acid, belongs to BCS classification class II, with high permeability, low solubility, poor solubility and low bioavailability in vivo. Indomethacin is a non-steroidal anti-inflammatory drug (NSAIDs) with anti-inflammatory, antipyretic and analgesic effects. It acts as an anti-inflammatory agent by reducing prostaglandin synthesis through the inhibition of cyclooxygenase, while the antipyretic effect is associated with the inhibition of prostaglandin synthesis in the inferior optic thalamus.
Indometacin CAS 53-86-1 of Chemical Properties
Melting point 158-162 °C
Boiling point 499.4±45.0 °C(Predicted)
density 1.2135 (rough estimate)
refractive index 1.6800 (estimate)
storage temp. Store at RT
solubility ethanol: 50 mg/mL, clear, yellow-green
pka 4.5(at 25ºC)
form White to off-white powder
Water Solubility Soluble in acet one (40 mg/mL - clear, yellow solution), ethanol (20 mg/mL), ether, castor oil; Soluble in chloro form (50 mg/mL - clear, yellow, extremely viscous solution); decomposed by strong alkali but stable in neutral or slightly acidic media; insoluble in water.
Sensitive Light Sensitive
Merck 14,4968
BRN 497341
Stability: Stable. Incompatible with strong oxidizing agents.
InChIKey CGIGDMFJXJATDK-UHFFFAOYSA-N
CAS DataBase Reference 53-86-1(CAS DataBase Reference)
NIST Chemistry Reference Indomethacin(53-86-1)
EPA Substance Registry System Indomethacin (53-86-1)
Shipping Terms | ||
By Express | By Air | By Sea |
Suitable for under 50kg Fast:3-4 days High cost Door to door service Easy to pick up the goods |
Suitable for more than 50kg Fast:3-4 days High cost Airport to airport Professional broker needed |
Suitable for more than 500kg Slow:15-30 days Low cost Port to port Professional broker needed |
Company Profile
Anhui puya biological technology co.,ltd was established in Hefei. Registered capital is 5 million. It is specialized in manufacture plant extract, API and chemicals raw material powder, food additives and oil. which are applied to skin care, healthcare, weight loss products, sex improvement, and pharmaceuticals. We will uphold honesty and pragmatic, innovative and enterprising service purposes, and provide a variety of quality services to our customers at abroad. It aims at supplying good product and comfort service. The strict quality control is to meet the customer's requirement, to get a highly praised and to be high quality supplier. If you have any question, or need samples, please feel free to contact us.
FAQ
Q1. What's the MOQ?
A: Usually 1 kg. It is based on the different product. Some are 1g and some are 1 ton. Please be free to consult our salesman.
Q2. What's the shipping time?
A: If in stock, we will ship it out immediately. By FedEx will be 3~5 days to you.
Q3. If I need less than the MOQ, is it possible?
A: Yes. Please be free to consult our salesman.
Q4. Can you supply the free sample?
A: Usually it is possible. but the shipping cost be paid by customers. It based on the different product. Please be free to consult our salesman.
Q5. How to store the product?
A: Store in cool and dry place. It must be in well closed containers. The shelf life will be 2 years.
Q6: What's your main payment method?
A: T/T, trade assurance, west union, money gram.
Q7: Do you have COA, MSDS, CO, Health certificate, form 9 or other certificate?
A: Yes, we have. pls be free to contact us to get updated one.
Suppliers with verified business licenses