CAS No.: | 439081-18-2 |
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Formula: | C24h25clfn5o3 |
EINECS: | 1308068-626-2 |
Type: | Pharmaceutical Intermediates |
Appearance: | Powder |
Quality: | Refined |
Samples: |
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Customization: |
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Puya Supply Afatinib / BIBW 2992 CAS 439081-18-2 Treatment Of Cancer
Product Name: Afatinib (BIBW 2992)
Synonyms: Tovok;BIBW 2992;N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-2-butenamide;Afatinb;(S)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dim;Afatinib(cis-trans isomerismtautomers);Afatinib(W.S);AFATINIB; BIBW2992;BIBW-2292
CAS: 439081-18-2
MF: C24H25ClFN5O3
MW: 485.94
EINECS: 1308068-626-2
Product Categories: API;Inhibitors
Mol File: 439081-18-2.mol
Afatinib is the first approved irreversible ErbB family blocker. the ErbB receptor family consists of four members: EGFR (ErbB1), HER2 (ErbB2), ErbB3 and ErbB4. members of the ErbB family interoperate with other ErbB family members in signaling, and abnormal ErbB family signaling is a key driver of cancer cell growth and proliferation . Afatinib has two targets, EGFR and HER2, which can irreversibly block the abnormalities of intracellular information transmission stimulated by the mutation of epidermal grow th fac tor receptor (EGFR) and the over-expression of human epidermal receptor 2 (HER2) tyrosine kinase, and permanently shut down the signaling channels on which cancer cells depend, so that cancer cells cannot grow and multiply, thus treating cancer.
Afatinib / BIBW 2992 CAS 439081-18-2 of Chemical Properties
Boiling point 676.9±55.0 °C(Predicted)
density 1.380
pka 12.06±0.43(Predicted)
CAS DataBase Reference 439081-18-2
Shipping Terms | ||
By Express | By Air | By Sea |
Suitable for under 50kg Fast:3-4 days High cost Door to door service Easy to pick up the goods |
Suitable for more than 50kg Fast:3-4 days High cost Airport to airport Professional broker needed |
Suitable for more than 500kg Slow:15-30 days Low cost Port to port Professional broker needed |
Company Profile
Anhui puya biological technology co.,ltd was established in Hefei. Registered capital is 5 million. It is specialized in manufacture plant extract, API and chemicals raw material powder, food additives and oil. which are applied to skin care, healthcare, weight loss products, sex improvement, and pharmaceuticals. We will uphold honesty and pragmatic, innovative and enterprising service purposes, and provide a variety of quality services to our customers at abroad. It aims at supplying good product and comfort service. The strict quality control is to meet the customer's requirement, to get a highly praised and to be high quality supplier. If you have any question, or need samples, please feel free to contact us.
FAQ
Q1. What's the MOQ?
A: Usually 1 kg. It is based on the different product. Some are 1g and some are 1 ton. Please be free to consult our salesman.
Q2. What's the shipping time?
A: If in stock, we will ship it out immediately. By FedEx will be 3~5 days to you.
Q3. If I need less than the MOQ, is it possible?
A: Yes. Please be free to consult our salesman.
Q4. Can you supply the free sample?
A: Usually it is possible. but the shipping cost be paid by customers. It based on the different product. Please be free to consult our salesman.
Q5. How to store the product?
A: Store in cool and dry place. It must be in well closed containers. The shelf life will be 2 years.
Q6: What's your main payment method?
A: T/T, trade assurance, west union, money gram.
Q7: Do you have COA, MSDS, CO, Health certificate, form 9 or other certificate?
A: Yes, we have. pls be free to contact us to get updated one.
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