| CAS No.: | 201530-41-8 |
|---|---|
| Formula: | C21h15n3o4 |
| EINECS: | 685-491-5 |
| Type: | Pharmaceutical Intermediates |
| Appearance: | Powder |
| Quality: | Refined |
| Samples: |
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| Customization: |
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Audited Supplier High Quality Deferasirox CAS 201530-41-8 With Good Price
Product Name: Deferasirox
Synonyms: Deferasirox(CGP-72670);4-[3,5-bis(6-oxocyclohexa-2,4-dien-1-ylidene)-1,2,4-triazolidin-1-yl]benzoic acid;Deferasirox(Exjade);Deferisirox;4-[3,5-bis(2-hydroxyphenyl);20kg;Deferasirox, >=99%;Deferasirox D8
CAS: 201530-41-8
MF: C21H15N3O4
MW: 373.36
EINECS: 685-491-5
Product Categories: Pharmaceutical intermediate;Aromatics;Chelating Agents & Ligands;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Chelating agent (iron);Aromatics Compounds;Exjade, ICL-670, ICL-670A, CGP-72670
Mol File: 201530-41-8.mol
Deferasirox: chemical name 4-[3,5-bis (2-hydroxyphenyl)-1,2,4-triazol-1-yl] benzoic acid, is a kind of iron chelator products studied and developed by the Novartis company (Swiss). It was the first routinely used oral iron agent approved by US FDA, allowed to be applied for the treatment of iron overloading caused by blood transfusion in patients (older than 2 years old) of chronic anemia. In Europe, it is recommended as the first-line treatment drug for patients older than 6-year-old who are suffering blood iron overload patients. In China, it is currently subject to clinical research; II, III clinical trials and pharmacokinetic studies have all shown that it has excellent safety and tolerability, and can significantly reduce the heart, liver iron load, easy to be accepted by the patient. At the same time, it also has pharmacological properties of antifungal (such as Mucor which can grow in iron-ricking environment), anti-cell proliferation, anti-malaria, antioxidant stress injury and anti-cytotoxicity induced apoptosis; it can be used for the treatment of hemochromatosis, delayed skin porphyria and other diseases.
Deferasirox CAS 201530-41-8 of Chemical Properties
Melting point 260-2620C
Boiling point 672.1±65.0 °C(Predicted)
density 1.40±0.1 g/cm3(Predicted)
storage temp. Keep in dark place,Inert atmosphere,2-8°C
solubility Soluble in DMSO (10 mg/ml)
pka pKa1 4.57, pKa2 8.71, pKa3 10.56 (Nick); Also reported in H2O/DMSO (CDMSO = 0.20) as pKa1 4.61, pKa2 10.12, pKa3 12.08 (Steinhauser)
form solid
color Off-white to white
Stability: Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
Function and Application of Deferasirox CAS 201530-41-8
| Shipping Terms | ||
| By Express | By Air | By Sea |
| Suitable for under 50kg Fast:3-4 days High cost Door to door service Easy to pick up the goods |
Suitable for more than 50kg Fast:3-4 days High cost Airport to airport Professional broker needed |
Suitable for more than 500kg Slow:15-30 days Low cost Port to port Professional broker needed |
Company Profile
Anhui puya biological technology co.,ltd was established in Hefei. Registered capital is 5 million. It is specialized in manufacture plant extract, API and chemicals raw material powder, food additives and oil. which are applied to skin care, healthcare, weight loss products, sex improvement, and pharmaceuticals. We will uphold honesty and pragmatic, innovative and enterprising service purposes, and provide a variety of quality services to our customers at abroad. It aims at supplying good product and comfort service. The strict quality control is to meet the customer's requirement, to get a highly praised and to be high quality supplier. If you have any question, or need samples, please feel free to contact us.
FAQ
Q1. What's the MOQ?
A: Usually 1 kg. It is based on the different product. Some are 1g and some are 1 ton. Please be free to consult our salesman.
Q2. What's the shipping time?
A: If in stock, we will ship it out immediately. By FedEx will be 3~5 days to you.
Q3. If I need less than the MOQ, is it possible?
A: Yes. Please be free to consult our salesman.
Q4. Can you supply the free sample?
A: Usually it is possible. but the shipping cost be paid by customers. It based on the different product. Please be free to consult our salesman.
Q5. How to store the product?
A: Store in cool and dry place. It must be in well closed containers. The shelf life will be 2 years.
Q6: What's your main payment method?
A: T/T, trade assurance, west union, money gram.
Q7: Do you have COA, MSDS, CO, Health certificate, form 9 or other certificate?
A: Yes, we have. pls be free to contact us to get updated one.
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