1) Name:Rifabutin 2) Purity: >99% 3) Cas no.:72559-06-9 4) Appearance: White powder 5) Supply Ability : 2Mt/Per Month 6) Storage: Store in a well-closed container away from moisture
Semisynthetic derivative of Rifamycin S that inhibits nucleic acid synthesis. An antibacterial (tuberculostatic).
Rifamycins are antibiotics that inhibit DNA-dependent RNA polymerases and are usually bactericidal against Gram-positive bacteria but bacteriostatic against Gram-negative bacteria. Rifamycins are also effective against Mycobacterium species, including M. tuberculosis. Rifabutin is a broad-spectrum rifamycin antibiotic that has applications against tuberculosis, H. pylori, M. avium complex, Chlamydia, and other bacteria. It is also useful in co-infections with human immunodeficiency virus, including tuberculosis.
A rifamycin derivative that acts against rifampicin resistant tuberculosis strains. The required concentration is only 1/40 of rifampicin. Toxicity is less than rifampicin. It is used in Japan for the treatment of atypical tuberculosis infection. It is also effective against drug-resistant leprosy. Prevention of AIDS mycobacterium tuberculosis infection. It is a spiral piperidine derivative of rifamycin and has 4 times stronger inhibitory effect on mycobacterium tuberculosis than forpinol. It is mainly used for pulmonary infection of mycobacterium, effective against rifampicin resistant tuberculosis strains, and can be used for drug resistance, retreatment of tuberculosis cases, intracellular mycobacterium infection and AIDS treatment. It is suitable for the treatment of all types of tuberculosis caused by mycobacterium tuberculosis in combination with other anti-tuberculosis drugs, and can also be used for the treatment of non-tuberculosis mycobacterium infection. This product is also suitable for patients with advanced HIV infection to prevent the spread of MAC. Rifambutin can be used for prevention and treatment of mycobacterium infection in patients with HIV. API: anti-tuberculosis, anti-HIV antibiotics