| CAS No.: | 1134-47-0 |
|---|---|
| Formula: | C10h12clno2 |
| EINECS: | 214-486-9 |
| Type: | Pharmaceutical Intermediates |
| Appearance: | Powder |
| Quality: | Refined |
| Samples: |
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| Customization: |
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Audited Supplier Puya Supply Pharmaceutical Grade Baclofene CAS 1134-47-0
Product Name: Baclofen
Synonyms: 4-Amino-3-(p-chlorophenyl)butyric acid;Benzenepropanoic acid, β-(aminomethyl)-4-chloro-;CIBA Ba 34647;DL-4-Amino-3-p-chlorophenylbutanoic acid;DL-Baclofen;Hydrocinnamic acid, β-(aminomethyl)-p-chloro- (7CI, 8CI);β-(4-Chlorophenyl)-γ-aminobutyric acid;β-p-Chlorophenyl-GABA
CAS: 1134-47-0
MF: C10H12ClNO2
MW: 213.66
EINECS: 214-486-9
Product Categories: KEMSTRO;GABA;Intermediates & Fine Chemicals;GABA/Glycine receptor;Amines;Aromatics;Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts;Active Pharmaceutical Ingredients;Pharmaceuticals;Used as a skeletal muscle relaxation of the spinal cord, sedatives;API;Piperazines ,Oxazolines/Oxazolidines
Mol File: 1134-47-0.mol
Baclofen is a γ-aminobutyric acid derivative. It is an antispasmodics class drugs acting on the central nervous system, the brain and spinal cord as a skeletal muscle relaxants and sedatives. It take antispasmodic effect by stimulating receptors to inhibit the release of excitatory amino acids such as glutamic acid, aspartic acid and thereby inhibiting the transfer of single and multi-synaptic reflex in central nervous system, brain and spinal cord. Clinically it has already been used as racemic agent for treating Muscle spasticity since mid-1960s. Recent studies have also found that this product can significantly reduce the symptoms of gastroesophageal reflux and alleviating related symptoms. It can also alleviate the dystonia of children and treat the urination dysfunction caused by central spinal cord injury. In addition, the intrathecal injection therapy of the product in clinical application can further improve the clinical efficacy, and make it possible to adjust drugs dosage which stabilizes the treatment effect. For the past 10 years, the clinical application of central muscle relaxant baclofen has made significant progress, particularly in accumulating a lot of experiences in the neurological rehabilitation treatment of reducing muscular tension and pain alleviation treatment.
Baclofene CAS 1134-47-0 of Chemical Properties
Melting point 208-210°C
Boiling point 364.3±32.0 °C(Predicted)
density 1.2069 (rough estimate)
refractive index 1.5500 (estimate)
storage temp. 2-8°C
solubility 1 M HCl: 50 mg/mL
form solid
pka pKa 3.87±0.1(H2O) (Uncertain)
color white to very faintly yellow
Water Solubility Soluble in dilute NaOH or dilute HCl. Soluble in water at approximately 4mg/ml at pH 7.6
Merck 14,937
CAS DataBase Reference 1134-47-0(CAS DataBase Reference)
NIST Chemistry Reference Baclofen(1134-47-0)
EPA Substance Registry System .beta.-(Aminomethyl)-4-chlorobenzenepropanoic acid (1134-47-0)
Function and Application of Baclofene CAS 1134-47-0
| Shipping Terms | ||
| By Express | By Air | By Sea |
| Suitable for under 50kg Fast:3-4 days High cost Door to door service Easy to pick up the goods |
Suitable for more than 50kg Fast:3-4 days High cost Airport to airport Professional broker needed |
Suitable for more than 500kg Slow:15-30 days Low cost Port to port Professional broker needed |
Company Profile
Anhui puya biological technology co.,ltd was established in Hefei. Registered capital is 5 million. It is specialized in manufacture plant extract, API and chemicals raw material powder, food additives and oil. which are applied to skin care, healthcare, weight loss products, sex improvement, and pharmaceuticals. We will uphold honesty and pragmatic, innovative and enterprising service purposes, and provide a variety of quality services to our customers at abroad. It aims at supplying good product and comfort service. The strict quality control is to meet the customer's requirement, to get a highly praised and to be high quality supplier. If you have any question, or need samples, please feel free to contact us.
FAQ
Q1. What's the MOQ?
A: Usually 1 kg. It is based on the different product. Some are 1g and some are 1 ton. Please be free to consult our salesman.
Q2. What's the shipping time?
A: If in stock, we will ship it out immediately. By FedEx will be 3~5 days to you.
Q3. If I need less than the MOQ, is it possible?
A: Yes. Please be free to consult our salesman.
Q4. Can you supply the free sample?
A: Usually it is possible. but the shipping cost be paid by customers. It based on the different product. Please be free to consult our salesman.
Q5. How to store the product?
A: Store in cool and dry place. It must be in well closed containers. The shelf life will be 2 years.
Q6: What's your main payment method?
A: T/T, trade assurance, west union, money gram.
Q7: Do you have COA, MSDS, CO, Health certificate, form 9 or other certificate?
A: Yes, we have. pls be free to contact us to get updated one.
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