| CAS No.: | 54-31-9 |
|---|---|
| Formula: | C12h11cln2o5s |
| EINECS: | 200-203-6 |
| Type: | Pharmaceutical Intermediates |
| Appearance: | Powder |
| Quality: | Refined |
| Samples: |
|---|
| Customization: |
|---|
Suppliers with verified business licenses
Audited Supplier High Quality Furosemide CAS 54-31-9 Use For Diuretics
Product Name: Furosemide
Synonyms: 4-CHLORO-N-FURFURYL-5-SULFAMOYLANTHRANILIC ACID;5-(AMINOSULPHONYL)-4-CHLORO-2-[(2-FURANYLMETHYL)AMINO]BENZOIC ACID;5-[AMINOSULFONYL]-4-CHLORO-2-[(2-FURANYLMETHYL)AMINO]BENZOIC ACID;LABOTEST-BB LT00244801;FUROSEMID;FUROSEMIDE;FRUSEMIDE;2-furfurylamino-4-chloro-5-sulfamoylbenzoic acid
CAS: 54-31-9
MF: C12H11ClN2O5S
MW: 330.74
EINECS: 200-203-6
Product Categories: LASIX;Other APIs;Ion transporter and other ion channel;GABA;Aromatics;API;Organics;Intermediates & Fine Chemicals;Pharmaceuticals;API's;Heterocycles;Sulfur & Seleni um Compounds
Mol File: 54-31-9.mol
Furosemide, is a class of efficient sulfonamide diuretics acting on the medullary loop of the ascending branch of the medulla,it has a strong and short-term diuretic effect,which can increase the excretion of water, sodium, chloride, potassium, calcium, magnesium, phosphate and so on. It Mainly inhibits Na + and Cl-reabsorption in medullary and cortex of the medullary loop ascending branch crude segment , it can promote the excretion of sodium, chloride and potassium and affect the formation of renal medullary high osmotic pressure,it can interfer the process of concentration and dilution of urine, and it can increase urine output. This product can inhibit the activity of prostaglandin decomposition enzyme ,make the content of prostaglandin E2 increase,it has effect on expansion of blood vessels, it also plays a role in the proximal tubule, glomerular filtration,it can increase renal blood flow,and adjust renal blood flow distribution,and reduce blood flow so that the cortex surface blood flow increases,it promotes diuresis, its effect is fast and strong, it is used for other diuretics invalid cases. Clinically it is used for the treatment of cardiac edema, renal edema, cirrhosis ascitic fluid, peripheral edema caused by dysfunction or vascular disorders , and it may contribute to an upper urinary tract stones excretion. Administration intravenously can treat brain edema, it also can accelerate the excretion of toxic substances in cerebral edema in poisoning . Note that when the diuretic furosemide is used, since the excretion of urine Cl-, Na +, K +, H + is increasing, while the excretion of HCO3-is not increasing, long-term repeated drug use or large quantities of drugs can cause low salt syndrome, low chlori ne and low potassium alkalosis.
Furosemide CAS 54-31-9 of Chemical Properties
Melting point 220 °C (dec.) (lit.)
Boiling point 582.1±60.0 °C(Predicted)
density 1.606
refractive index 1.6580 (estimate)
Fp 11 °C
storage temp. 2-8°C
solubility Practically insoluble in water, soluble in aceto ne, sparingly soluble in ethanol (96 per cent), practically insoluble in methylene chlorid e. It dissolves in dilute solutions of alkali hydroxides.
form powder
pka pKa 3.8 (Uncertain)
color White to Off-White
Water Solubility Soluble in aceto ne, DMF or methan ol. Slightly soluble in water
Merck 14,4309
Stability: Stable, but light sensitive, air sensitive and hygroscopic. Incompatible with strong oxidizing agents.
InChIKey ZZUFCTLCJUWOSV-UHFFFAOYSA-N
CAS DataBase Reference 54-31-9(CAS DataBase Reference)
IARC 3 (Vol. 50) 1990
EPA Substance Registry System Furosemide (54-31-9)
Function and Application of Furosemide CAS 54-31-9
| Shipping Terms | ||
| By Express | By Air | By Sea |
| Suitable for under 50kg Fast:3-4 days High cost Door to door service Easy to pick up the goods |
Suitable for more than 50kg Fast:3-4 days High cost Airport to airport Professional broker needed |
Suitable for more than 500kg Slow:15-30 days Low cost Port to port Professional broker needed |
Company Profile
Anhui puya biological technology co.,ltd was established in Hefei. Registered capital is 5 million. It is specialized in manufacture plant extract, API and chemicals raw material powder, food additives and oil. which are applied to skin care, healthcare, weight loss products, sex improvement, and pharmaceuticals. We will uphold honesty and pragmatic, innovative and enterprising service purposes, and provide a variety of quality services to our customers at abroad. It aims at supplying good product and comfort service. The strict quality control is to meet the customer's requirement, to get a highly praised and to be high quality supplier. If you have any question, or need samples, please feel free to contact us.
FAQ
Q1. What's the MOQ?
A: Usually 1 kg. It is based on the different product. Some are 1g and some are 1 ton. Please be free to consult our salesman.
Q2. What's the shipping time?
A: If in stock, we will ship it out immediately. By FedEx will be 3~5 days to you.
Q3. If I need less than the MOQ, is it possible?
A: Yes. Please be free to consult our salesman.
Q4. Can you supply the free sample?
A: Usually it is possible. but the shipping cost be paid by customers. It based on the different product. Please be free to consult our salesman.
Q5. How to store the product?
A: Store in cool and dry place. It must be in well closed containers. The shelf life will be 2 years.
Q6: What's your main payment method?
A: T/T, trade assurance, west union, money gram.
Q7: Do you have COA, MSDS, CO, Health certificate, form 9 or other certificate?
A: Yes, we have. pls be free to contact us to get updated one.
Suppliers with verified business licenses
Audited Supplier 
){kind=link}
){kind=link}