High Quality Mupirocin CAS 12650-69-0 Treatment of Bacterial Skin Infections

• CAS No.: 12650-69-0
• Formula: C26h44o9
• EINECS: 603-145-3
• Type: Pharmaceutical Intermediates
• Appearance: Powder
• Quality: Refined
• Model NO.: 008
• Colour: White
• Grade: Pharm
• Spec.: USP, Ep, Cp
• MOQ: 1kg
• Shipping Time: After Payment
• Transport Package: 1kg/Aluminum Bag or 25kg/Drum
• Specification: 99% min
• Trademark: Puya
• Origin: China
• Production Capacity: 5000kilogram/Month

Product Description

High Quality Mupirocin CAS 12650-69-0 Treatment Of Bacterial Skin Infections

Product Name:    Mupirocin
Synonyms:    MUPIROCIN;MUPIROCIN CALCIUM;L-talo-Non-2-enonic acid, 5,9-anhydro-2,3,4,8-tetradeoxy-8-(2S,3S)-3-(1S,2S)-2-hydroxy-1-methylpropyloxiranylmethyl-3-methyl-, 8-carboxyoctyl ester, (2E)-;MUPIROCIN,USP;Bactoderm;Bactroban Ointment;L-talo-Non-2-enonic acid, 5,9-anhydro-2,3,4,8-tetradeoxy-8-[[(2S,3S)-3-[(1S,2S)-2-hydroxy-1-methylpropyl]oxiranyl]methyl]-3-methyl-, 8-carboxyoctyl ester, (2E)- (9CI);L-talo-Non-2-enonic acid, 5,9-anhydro-2,3,4,8-tetradeoxy-8-[[3-(2-hydroxy-1-methylpropyl)oxiranyl]methyl]-3-methyl-, 8-carboxyoctyl ester, [2E,8[2S,3S(1S,2S)]]-
CAS:    12650-69-0
MF:    C26H44O9
MW:    500.62
EINECS:    603-145-3
Product Categories:    Intermediates & Fine Chemicals;Pharmaceuticals;Active Pharmaceutical Ingredients;Chiral Reagents;Heterocycles;Inhibitors;API
Mol File:    12650-69-0.mol



Mupirocin, also known as Pseudomonas aeruginosa A, is an ideal antimicrobial agent for skin surface, which was marketed by GlaxoSmithKline in 1985 under the trade name of Bactroban. The FDA approved the drug for use in the U.S. in 1987, and China approved the manufacture and sale of the drug by China-US SK in 1993. Mupirocin is mainly used for the prevention and treatment of bacterial skin infections caused by gram-positive cocci. Mupirocin is mainly used for the prevention and treatment of bacterial skin infections caused by Gram-positive cocci, such as primary skin infections like impetigo, boils and folliculitis, and secondary skin infections like eczema co-infection, ulcer co-infection and trauma co-infection. The main mechanism of antibacterial action of mupirocin is to inhibit protein synthesis in bacteria.

Mupirocin CAS 12650-69-0 of Chemical Properties
Melting point     77-780C
alpha     D20 -19.3° (c = 1 in methan ol)
Boiling point     672ºC
density     1.183±0.06 g/cm3(Predicted)
Fp     >110°(230°F)
storage temp.     Inert atmosphere,Store in freezer, under -20°C
solubility     H2O: 12 mg/mL, soluble
pka    4.78±0.10(Predicted)
form     solid
color     white to tan
optical activity    [α]/D -15.7 to -20°, c = 1 in methan ol
Water Solubility     Soluble in DMSO or methan ol. Sparingly soluble in water
λmax    222nm(EtOH)(lit.)
Merck     14,6302
Stability:    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
InChIKey    MINDHVHHQZYEEK-HBBNESRFSA-N
CAS DataBase Reference    12650-69-0(CAS DataBase Reference)

Function and Application of Mupirocin CAS 12650-69-0
1. Mupirocin is a topical antibiotics. Stops the synthesis of all intracellular isoleucine-containing proteins by reversibly binding to isoleucine-transfer RNA synthase and thus preventing isoleucine participation. Used for acute primary bacterial skin infections, such as folliculitis and impetigo.
2. Mupirocin, is a major component of the pseudomonic acid, an antibiotic complex produced by Pseudomonas fluorescens NCIB 10586. Topical antibacterial.
3. Pseudomonic acid is a potent antibiotic produced by Pseudomonas fluorescens, reported by Fuller et al. in 1971. Pseudomonic acid has broad spectrum activity against Gram positive bacteria and was approved for topical human use in 1985. Pseudomonic acid acts as a potent and selective inhibitor of isoleucyl-tRNA synthetase.
4. Mupirocin is an antibiotic inhibitor of isoleucyl-tRNA synthetase


Packing And Shipping
1.Preferentially DHL, FedEX or TNT for quantity less than 50kg, air shipping for 100kg above, sea shipping for quantity over 500kg.
2.For customers from Russia,Mexico,Turkey,Solvenia,Romania,etc,before placing an order,please kindly confirm if you can make clearance when goods reach your customs.

Shipping Terms
By Express	By Air	By Sea
Suitable for under 50kg Fast:3-4 days High cost Door to door service Easy to pick up the goods	Suitable for more than 50kg Fast:3-4 days High cost Airport to airport Professional broker needed	Suitable for more than 500kg Slow:15-30 days Low cost Port to port Professional broker needed

 

Company Profile
Anhui puya biological technology co.,ltd was established in Hefei. Registered capital is 5 million. It is specialized in manufacture plant extract, API and chemicals raw material powder, food additives and oil. which are applied to skin care, healthcare, weight loss products, sex improvement, and pharmaceuticals. We will uphold honesty and pragmatic, innovative and enterprising service purposes, and provide a variety of quality services to our customers at abroad. It aims at supplying good product and comfort service. The strict quality control is to meet the customer's requirement, to get a highly praised and to be high quality supplier. If you have any question, or need samples, please feel free to contact us.

FAQ
Q1. What's the MOQ?
A: Usually 1 kg.  It is based on the different product. Some are 1g and some are 1 ton. Please be free to consult our salesman.
 
Q2. What's the shipping time?
A: If in stock, we will ship it out immediately.  By FedEx will be 3~5 days to you.
 
Q3. If I need less than the MOQ, is it possible?
A: Yes. Please be free to consult our salesman.
 
Q4. Can you supply the free sample?
A: Usually it is possible. but the shipping cost be paid by customers. It based on the different product. Please be free to consult our salesman.
 
Q5. How to store the product?
A: Store in cool and dry place. It must be in well closed containers. The shelf life will be 2 years.
 
Q6: What's your main payment method?
A: T/T, trade assurance, west union, money gram.
 
Q7: Do you have COA, MSDS, CO, Health certificate, form 9 or other certificate?
A: Yes, we have. pls be free to contact us to get updated one.