| CAS No.: | 78415-72-2 |
|---|---|
| Formula: | C12h9n3o |
| EINECS: | 278-903-6 |
| Type: | Pharmaceutical Intermediates |
| Appearance: | Powder |
| Quality: | Refined |
| Samples: |
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| Customization: |
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Audited Supplier Top Quality Milrinone CAS 78415-72-2 Treatment Of Heart Failure
Product Name: Milrinone
Synonyms: Corotrope;Milrila;3-CYANO-6-METHYL-5-(4-PYRIDYL)-2-PYRIDONE;6-METHYL-5-(4-PYRIDYL)-2-PYRIDONE-3-CARBONITRILE;1,6-DIHYDRO-2-METHYL-6-OXO-(3,4'-BIPYRIDINE)-5-CARBONITRILE;Primacor;6-Methyl-2-oxo-5-pyridin-4-yl-1H-pyridine-3-carbonitrile;YM-018
CAS: 78415-72-2
MF: C12H9N3O
MW: 211.22
EINECS: 278-903-6
Product Categories: Cyclic Nucleotide related;Pharmaceutical Intermediate;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Pyridines;Active Pharmaceutical Ingredients;API;Aromatics;CELEXA
Mol File: 78415-72-2.mol
Milrinone, also known as bipyridine ketone, methyl cyani de topiramate ketone, is a drug for the treatment of heart failure ,it is a homolog of amrinone, having positive inotropic and vasodilatory effects, its mechanism of action is the same as ammoni a milrinone , but the strength of its effect is 10 to 30 times of amrinone,without side effects of reducing platelets,it is well tolerated. Oral or intravenous way has a good effect, it can increase cardiac output and cardiac index, reduce left ventricular end diastolic pressure, pulmonary wedge pressure and right atrial pressure, it has no significant effect on blood pressure and heart rate,it takes effect within 0.5 hours after oral administration,and achieves to maximum effect after 1 to 3 hours , the half-life is 2 hours, the effect can be maintained for 4-6 hours, it is mainly metabolically inactivated in the liver , 80% of it is excreted unchanged in the urine. It is clinically used in the treatment of various acute and chronic heart failure,it is effective in digitalis and diuretics invalid refractory heart failure . This product is the same as amrinone, significant short-term effect, long-term efficacy remains to be further confirmed, but the side effects are little.
Milrinone CAS 78415-72-2 of Chemical Properties
Melting point >3000C
Boiling point 350.9°C (rough estimate)
density 1.1922 (rough estimate)
refractive index 1.5700 (estimate)
storage temp. 2-8°C
solubility DMSO: >10 mg/mL
form powder
pka 7.21±0.10(Predicted)
color off-white
Water Solubility Soluble in DMSO. Insoluble in water.
Merck 14,6197
Stability: Stable. Incompatible with strong oxidizing agents.
InChIKey FYEJSUDMDUIMKJ-UHFFFAOYSA-N
CAS DataBase Reference 78415-72-2(CAS DataBase Reference)
Function and Application of Milrinone CAS 78415-72-2
| Shipping Terms | ||
| By Express | By Air | By Sea |
| Suitable for under 50kg Fast:3-4 days High cost Door to door service Easy to pick up the goods |
Suitable for more than 50kg Fast:3-4 days High cost Airport to airport Professional broker needed |
Suitable for more than 500kg Slow:15-30 days Low cost Port to port Professional broker needed |
Company Profile
Anhui puya biological technology co.,ltd was established in Hefei. Registered capital is 5 million. It is specialized in manufacture plant extract, API and chemicals raw material powder, food additives and oil. which are applied to skin care, healthcare, weight loss products, sex improvement, and pharmaceuticals. We will uphold honesty and pragmatic, innovative and enterprising service purposes, and provide a variety of quality services to our customers at abroad. It aims at supplying good product and comfort service. The strict quality control is to meet the customer's requirement, to get a highly praised and to be high quality supplier. If you have any question, or need samples, please feel free to contact us.
FAQ
Q1. What's the MOQ?
A: Usually 1 kg. It is based on the different product. Some are 1g and some are 1 ton. Please be free to consult our salesman.
Q2. What's the shipping time?
A: If in stock, we will ship it out immediately. By FedEx will be 3~5 days to you.
Q3. If I need less than the MOQ, is it possible?
A: Yes. Please be free to consult our salesman.
Q4. Can you supply the free sample?
A: Usually it is possible. but the shipping cost be paid by customers. It based on the different product. Please be free to consult our salesman.
Q5. How to store the product?
A: Store in cool and dry place. It must be in well closed containers. The shelf life will be 2 years.
Q6: What's your main payment method?
A: T/T, trade assurance, west union, money gram.
Q7: Do you have COA, MSDS, CO, Health certificate, form 9 or other certificate?
A: Yes, we have. pls be free to contact us to get updated one.
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