Puya Supply Flurbiprofen CAS 5104-49-4 Treatment of Rheumatoid Arthritis

• CAS No.: 5104-49-4
• Formula: C15h13fo2
• EINECS: 225-827-6
• Type: Pharmaceutical Intermediates
• Appearance: Powder
• Quality: Refined
• Model NO.: PY202211151334
• Colour: White
• Transport Package: 1kg/Aluminum Bag or 25kg/Drum
• Specification: 99% min
• Trademark: Puya
• Origin: China
• Production Capacity: 5000kilogram/Month

Product Description

Puya Supply Flurbiprofen CAS 5104-49-4 Treatment Of Rheumatoid Arthritis

Product Name:    Flurbiprofen
Synonyms:    1'-biphenyl)-4-aceticacid,2-fluoro-alpha-methyl-(;1'-biphenyl]-4-aceticacid,2-fluoro-alpha-methyl-[;2-(2-Fluoro-4-biphenyl)propionicacid;2-(2-fluoro-4-biphenylyl)propionicacid;2-fluoro-alpha-methyl-4-biphenylaceticaci;(+/-)-FLURBIPROFEN;FLURBIPROFEN;ANSAID
CAS:    5104-49-4
MF:    C15H13FO2
MW:    244.27
EINECS:    225-827-6
Product Categories:    ANSAID;Other APIs;Intermediates & Fine Chemicals;API's;Aromatics;API;Pharmaceuticals
Mol File:    5104-49-4.mol




Flibanseri n , also known as flurbiprofen, flurbiprofen, is a potent Phenylalanine anti-inflammatory and antipyretic analgesics,it can inhibit prostaglandin synthesizing cyclooxygenase to have analgesic, anti-inflammatory and antipyretic effects. Its anti-inflammatory and analgesic effects are 250 times and 50 times of aspirin (also known as acetylsalicylic acid) . The oral absorption is rapid , peak plasma concentration achieves after 1.5 hours , half-life is 3.5 hours, it has wide tissue distribution, PPB is 99.4%, it can compete with drugs having a high plasma protein binding rate to bind plasma protein .it Metabolizes in the liver and becomes flurbiprofen hydroxy and its aldehyde acid conjugates. T1/2 is 3.5 h. Urine and fecal excretion,account for approximately 60% and 40% respectively . Age has no effect on drug metabolism. It is Mainly used for rheumatoid arthritis, rheumatoid arthritis, ankylosing spondylitis, osteoarthritis. It is also used in preventing aphakic cystoid patchy edema After surgical removal of the lens, inhibiting pupillary constrictionsurgery, treatment of inflammation after cataract and trabeculoplasty arg on laser eye surgery. It Also applies to pain caused by some other reasons such as trauma, sprains, surgery.

Flurbiprofen CAS 5104-49-4 of Chemical Properties
Melting point     110-112 °C(lit.)
Boiling point     376.2±30.0 °C(Predicted)
density     1.1795 (estimate)
storage temp.     Sealed in dry,Room Temperature
solubility     methano l: soluble50mg/mL
form     White solid
pka    pKa 3.80(H2O) (Uncertain)
color     white to off-white
Water Solubility     8mg/L(room temperature)
Merck     14,4199
InChIKey    SYTBZMRGLBWNTM-UHFFFAOYSA-N
CAS DataBase Reference    5104-49-4(CAS DataBase Reference)
EPA Substance Registry System    [1,1'-Biphenyl]-4-acetic acid, 2-fluoro-?-methyl- (5104-49-4)


Function and Application of Flurbiprofen CAS 5104-49-4

1. Flurbiprofen is anti-inflammatory drug for chronic arthritis and pain, inflammation of Deformation joint disease , and pain after surgery and tooth extraction. Mouse oral LD50 of 140mg/kg, rats 640-800mg/kg.

Packing And Shipping
1.Preferentially DHL, FedEX or TNT for quantity less than 50kg, air shipping for 100kg above, sea shipping for quantity over 500kg.
2.For customers from Russia,Mexico,Turkey,Solvenia,Romania,etc,before placing an order,please kindly confirm if you can make clearance when goods reach your customs.

Shipping Terms
By Express	By Air	By Sea
Suitable for under 50kg Fast:3-4 days High cost Door to door service Easy to pick up the goods	Suitable for more than 50kg Fast:3-4 days High cost Airport to airport Professional broker needed	Suitable for more than 500kg Slow:15-30 days Low cost Port to port Professional broker needed

 

Company Profile
Anhui puya biological technology co.,ltd was established in Hefei. Registered capital is 5 million. It is specialized in manufacture plant extract, API and chemicals raw material powder, food additives and oil. which are applied to skin care, healthcare, weight loss products, sex improvement, and pharmaceuticals. We will uphold honesty and pragmatic, innovative and enterprising service purposes, and provide a variety of quality services to our customers at abroad. It aims at supplying good product and comfort service. The strict quality control is to meet the customer's requirement, to get a highly praised and to be high quality supplier. If you have any question, or need samples, please feel free to contact us.

FAQ
Q1. What's the MOQ?
A: Usually 1 kg.  It is based on the different product. Some are 1g and some are 1 ton. Please be free to consult our salesman.
 
Q2. What's the shipping time?
A: If in stock, we will ship it out immediately.  By FedEx will be 3~5 days to you.
 
Q3. If I need less than the MOQ, is it possible?
A: Yes. Please be free to consult our salesman.
 
Q4. Can you supply the free sample?
A: Usually it is possible. but the shipping cost be paid by customers. It based on the different product. Please be free to consult our salesman.
 
Q5. How to store the product?
A: Store in cool and dry place. It must be in well closed containers. The shelf life will be 2 years.
 
Q6: What's your main payment method?
A: T/T, trade assurance, west union, money gram.
 
Q7: Do you have COA, MSDS, CO, Health certificate, form 9 or other certificate?
A: Yes, we have. pls be free to contact us to get updated one.