High Purity Tolnaftate CAS 2398-96-1 for Anti Skin Fungus

• CAS No.: 2398-96-1
• Formula: C19h17nos
• EINECS: 219-266-6
• Type: Pharmaceutical Intermediates
• Appearance: Powder
• Quality: Refined
• Model NO.: PY202211202056
• Colour: White
• Grade: Pharm
• Spec: USP, Ep, Cp
• MOQ: 1kg
• Delivery Time: After Payment
• Transport Package: 1kg/Aluminum Bag or 25kg/Drum
• Specification: 99% min
• Trademark: Puya
• Origin: China
• Production Capacity: 5000kilogram/Month

Product Description

High Purity Tolnaftate CAS 2398-96-1 For Anti Skin Fungus

Product Name:    Tolnaftate
Synonyms:    2-naphthyl n-methyl-n-(3-tolyl)thionocarbamate;METHYL 3-TOLYLTHIOCARBAMIC ACID O-NAPHTHALEN-2-YL ESTER;METHYL-[3-METHYLPHENYL]-CARBAMOTHIOIC ACID O-2-NAPHTHYL ESTER;Aftate;Carbamothioic acid, methyl(3-methylphenyl)-, O-2-naphthalenyl ester;Carbanilic acid, m,N-dimethylthio-, O-2-naphthyl ester;Carbanilic acid, N,m-dimethylthio-, O-2-naphthyl ester;Chinofungin
CAS:    2398-96-1
MF:    C19H17NOS
MW:    307.41
EINECS:    219-266-6
Product Categories:    Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals;TINACTIN
Mol File:    2398-96-1.mol

Tolnaftate is the first marketed thiocarbamate antifungal drug. It can inhibit squalene epoxidase in the fungal ergosterol synthesis pathway, resulting in the blockage of ergosterol synthesis. Ergosterol is an important component of the fungal cell membrane and is essential for the growth and survival of the fungus. It is mostly believed that tolnaftate has only antibacterial activity.

Tolnaftate CAS 2398-96-1 of Chemical Properties
Melting point     110.5-111.5°C
Boiling point     453.4±38.0 °C(Predicted)
density     1.1328 (rough estimate)
refractive index     1.6970 (estimate)
storage temp.     Sealed in dry,2-8°C
solubility     Soluble in chloro form at 50 mg/ml. Sparingly soluble in ethanol or methan ol
form     powder
pka    -0.35±0.50(Predicted)
color     white to off-white
Water Solubility     <0.1 g/100 mL at 22 ºC
λmax    258nm(MeOH)(lit.)
Merck     14,9519
InChIKey    FUSNMLFNXJSCDI-UHFFFAOYSA-N
NIST Chemistry Reference    Tolnaftate(2398-96-1)
EPA Substance Registry System    Tolnaftate (2398-96-1)

Function and Application of Tolnaftate CAS 2398-96-1

1. Tolnaftate is used to study the mechanism of ergosterol (sterol) biosynthesis at the rate-limiting step of squalene epoxidase inhibition. Tolnaftate is clinically used to treat cutaneous infections such as athletes foot, jock itch, and ringworm. It also has been used as a comparator compound for antifungal efficiency studies.
2. antifungal for cutaneous infections.
Tolnaftate (Aftate, Tinactin, etc.) is an odorless and nonstaining synthetic antifungal agent whose exact mechanism of action is unknown. It is effective against dermatophytes and P. orbiculare and Pityrosporum ovale. It is ineffective against C. albicans and bacteria.
3. Tolnaftate topical is used to treat skin infections such as athlete's foot, jock itch, and ringworm infections. Tolnaftate is also used, along with other antifungals, to treat infections of the nails, scalp, palms, and soles of the feet.


Packing And Shipping
1.Preferentially DHL, FedEX or TNT for quantity less than 50kg, air shipping for 100kg above, sea shipping for quantity over 500kg.
2.For customers from Russia,Mexico,Turkey,Solvenia,Romania,etc,before placing an order,please kindly confirm if you can make clearance when goods reach your customs.

Shipping Terms
By Express	By Air	By Sea
Suitable for under 50kg Fast:3-4 days High cost Door to door service Easy to pick up the goods	Suitable for more than 50kg Fast:3-4 days High cost Airport to airport Professional broker needed	Suitable for more than 500kg Slow:15-30 days Low cost Port to port Professional broker needed

 

Company Profile
Anhui puya biological technology co.,ltd was established in Hefei. Registered capital is 5 million. It is specialized in manufacture plant extract, API and chemicals raw material powder, food additives and oil. which are applied to skin care, healthcare, weight loss products, sex improvement, and pharmaceuticals. We will uphold honesty and pragmatic, innovative and enterprising service purposes, and provide a variety of quality services to our customers at abroad. It aims at supplying good product and comfort service. The strict quality control is to meet the customer's requirement, to get a highly praised and to be high quality supplier. If you have any question, or need samples, please feel free to contact us.

FAQ
Q1. What's the MOQ?
A: Usually 1 kg.  It is based on the different product. Some are 1g and some are 1 ton. Please be free to consult our salesman.
 
Q2. What's the shipping time?
A: If in stock, we will ship it out immediately.  By FedEx will be 3~5 days to you.
 
Q3. If I need less than the MOQ, is it possible?
A: Yes. Please be free to consult our salesman.
 
Q4. Can you supply the free sample?
A: Usually it is possible. but the shipping cost be paid by customers. It based on the different product. Please be free to consult our salesman.
 
Q5. How to store the product?
A: Store in cool and dry place. It must be in well closed containers. The shelf life will be 2 years.
 
Q6: What's your main payment method?
A: T/T, trade assurance, west union, money gram.
 
Q7: Do you have COA, MSDS, CO, Health certificate, form 9 or other certificate?
A: Yes, we have. pls be free to contact us to get updated one.