Caffeic Acid Phenethyl Ester Powder Phenethyl Caffeate CAS 104594-70-9
Product name:Caffeic acid phenethyl ester
Synonyms: 3,4-Dihydroxycinnamic acid; 2-Propenoic acid, 3-(3,4-dihydroxyphenyl); 3,4-Dihydroxybenzeneacrylic acid;3-(3,4-Dihydroxyphenyl)-2-propenoic acid;4-(2',Carboxyvinyl)-1,2-dihydroxybenzene
Molecular formula: C9H8O4
Molecular weight: 180.16
CAS No.: 331-39-5
Melt Point: 194-198°C
Solubility: Soluble in water. (> 0.65 ug/ml at 25.0 C)
Appearance: White Solid
Caffeic acid phenethyl ester is abbreviated as CPAE, which is one of the main active components of propolis, which is effective for herpes viruses. Other viruses inhibited by the components of propolis include adenovirus and influenza virus. The CAPE, quercetin, prenyl ester, rhamnetin, galangin, glycosides, polysaccharides and other substances in propolis have anti-cancer activity, can inhibit the proliferation of tumor cells, and have a certain toxic and killing effect on cancer cells. , And CAPE has specific lethality on tumor cells. Jeng et al. believe that CAPE participates in inducing the death of natural cells, and has cytotoxic effects on malignant diseased tissues. CAPE can improve the tumor factor (12-0-myristyl alcohol-13-ethyl) at a very small concentration. Acidic acid ester) caused by inflammation syndrome reaction. The structure of caffeic acid phenethyl ester contains 0-dihydroxy phenyl structure, which is a common structure for scavenging free radicals, and there are two ortho-phenolic hydroxyl groups, which make the electron density on the benzene ring high and extremely It is easy to auto-oxidize and shows color. Bors et al. reported that the 0-dihydroxybenzene ring structure plays an important role in the antioxidant effect of flavonoids. The chemical components of propolis in different regions are different, so the CAPE content is also different. Studies have shown that the CAPE content of propolis produced in China is relatively high, reaching 15-25mg/g, while the propolis produced in Brazil does not contain CAPE. The laboratory uses caffeic acid and β-bromoethylbenzene as raw materials and potassium phosphate as a catalyst to synthesize caffeic acid phenethyl ester with a yield of up to 60%.
Function
1. Caffeic acid phenethyl ester has been shown to inhibit carcinogenesis, although other experiments show possible carcinogenic effects. It is also known as an antioxidant in vitro and also in vivo.
2. Caffeic acid phenethyl ester also shows immunomodulatory and anti-inflammatory activity.
3. Caffeic acid phenethyl ester outperformed the other antioxidants.
Application
Caffeic acid phenethyl ester used in Cosmetic Grade, Feed Grade, Food Grade, Medicine Grade
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