High Quality Valsartan CAS 137862-53-4 Treatment of Hypertension

• CAS No.: 137862-53-4
• Formula: C24h29n5o3
• EINECS: 1592732-453-0
• Type: Pharmaceutical Intermediates
• Appearance: Powder
• Quality: Refined
• Colour: White
• Transport Package: 1kg/Aluminum Bag or 25kg/Drum
• Specification: 99% min
• Trademark: Puya
• Origin: China
• Production Capacity: 5000kilogram/Month

Product Description

High Quality Valsartan CAS 137862-53-4 Treatment Of Hypertension

Product Name:    Valsartan
Synonyms:    L-Valine, N-(1-oxopentyl)-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-;Ambroxol Hydrochloride Imp.D;3-Methyl-2-[pentanoyl-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]amino]-butanoic aci;(S)-N-(1-carboxy-2-methyl-prop-1-yl)-N-pentanoyl-N-[(2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl]amine;(S)-2-(N-((2'-(1H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)pentanamido)-3-methylbutanoic aci;VALSARTAN IMP C;Valsartan,99%e.e.;N-(1-OXOPENTYL)-N-[[2'-(1H-TETRAZOL-5-YL)[1,1'-BIPHENYL]-4-YL]METHYL]-L-VALINE
CAS:    137862-53-4
MF:    C24H29N5O3
MW:    435.52
EINECS:    1592732-453-0
Product Categories:    Inhibitors;Aromatics;APIs;Intermediates & Fine Chemicals;Chiral Reagents;Heterocycles;Active Pharmaceutical Ingredients;Antihypertensive;Pharmaceuticals;API's;API Reference Standard Free Base API;DIOVAN;API
Mol File:    137862-53-4.mol


Valsartan is a specific angiotensin II (AT1) receptor antagonist and another non-skin AT1 receptor antagonist used in clinical practice after cloxacin, which plays a key role in regulating systemic blood pressure and maintaining electrolyte fluid balance. It selectively acts on the AT1 receptor subtype and blocks the binding of Ang II to AT1 receptor (its specific antagonism of AT1 receptor is about 20,000 times greater than that of AT2 receptor), thus inhibiting vasoconstriction and aldosterone release and producing hypotensive effects, but not inhibiting aldosterone release due to potassium ion (K+). The antihypertensive effect is better than enalapril, and is suitable for the treatment of antihypertensive, mild to moderate primary hypertension, especially for secondary hypertension due to renal damage, and can significantly reduce proteinuria in hypertensive patients with diabetes or normal renal function, and has a renal protective effect of promoting uric acid and urinary sodium excretion. It is also indicated to reduce cardiovascular mortality in patients at high risk after heart attack (left ventricular failure or left ventricular dysfunction).

Valsartan CAS 137862-53-4 of Chemical Properties
Melting point     116-117°C
Boiling point     684.9±65.0 °C(Predicted)
density     1.212±0.06 g/cm3(Predicted)
storage temp.     2-8°C
solubility     DMSO: ≥20mg/mL
pka    3.56±0.10(Predicted)
form     powder
color     white to tan
optical activity    [α]/D -55 to -70°, c = 1 in methan ol
Water Solubility     84.99mg/L(25 ºC)
Merck     14,9916
Stability:    Hygroscopic
InChIKey    ACWBQPMHZXGDFX-QFIPXVFZSA-N
CAS DataBase Reference    137862-53-4(CAS DataBase Reference)
EPA Substance Registry System    L-Valine, N-(1-oxopentyl)-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]- (137862-53-4)

Function and Application of Valsartan CAS 137862-53-4
1. Valsartan is an antihypertensive drugs. Non-peptide angiotensin II AT1-receptor antagonist. Used to treat hypertension.
2. Valsartan is used as a first-line drug for the treatment of uncomplicated hypertension, isolated systolic hypertension, and left ventricular hypertrophy. Valsartan is a clinically widely used antihypertensive agent with the advantages of low side effects and good tolerability, and can also be used for the treatment of hypertension in patients with diabetes and renal disease.


Packing And Shipping
1.Preferentially DHL, FedEX or TNT for quantity less than 50kg, air shipping for 100kg above, sea shipping for quantity over 500kg.
2.For customers from Russia,Mexico,Turkey,Solvenia,Romania,etc,before placing an order,please kindly confirm if you can make clearance when goods reach your customs.

Shipping Terms
By Express	By Air	By Sea
Suitable for under 50kg Fast:3-4 days High cost Door to door service Easy to pick up the goods	Suitable for more than 50kg Fast:3-4 days High cost Airport to airport Professional broker needed	Suitable for more than 500kg Slow:15-30 days Low cost Port to port Professional broker needed

 

Company Profile
Anhui puya biological technology co.,ltd was established in Hefei. Registered capital is 5 million. It is specialized in manufacture plant extract, API and chemicals raw material powder, food additives and oil. which are applied to skin care, healthcare, weight loss products, sex improvement, and pharmaceuticals. We will uphold honesty and pragmatic, innovative and enterprising service purposes, and provide a variety of quality services to our customers at abroad. It aims at supplying good product and comfort service. The strict quality control is to meet the customer's requirement, to get a highly praised and to be high quality supplier. If you have any question, or need samples, please feel free to contact us.

FAQ
Q1. What's the MOQ?
A: Usually 1 kg.  It is based on the different product. Some are 1g and some are 1 ton. Please be free to consult our salesman.
 
Q2. What's the shipping time?
A: If in stock, we will ship it out immediately.  By FedEx will be 3~5 days to you.
 
Q3. If I need less than the MOQ, is it possible?
A: Yes. Please be free to consult our salesman.
 
Q4. Can you supply the free sample?
A: Usually it is possible. but the shipping cost be paid by customers. It based on the different product. Please be free to consult our salesman.
 
Q5. How to store the product?
A: Store in cool and dry place. It must be in well closed containers. The shelf life will be 2 years.
 
Q6: What's your main payment method?
A: T/T, trade assurance, west union, money gram.
 
Q7: Do you have COA, MSDS, CO, Health certificate, form 9 or other certificate?
A: Yes, we have. pls be free to contact us to get updated one.