Antiviral Powder Trifluridine CAS 70-00-8 for Anti-Fection

• CAS No.: 70-00-8
• Formula: C10h11f3n2o5
• EINECS: 200-722-8
• Type: Pharmaceutical Intermediates
• Appearance: Powder
• Quality: Refined
• Model NO.: PY202210261711
• Colour: White
• Transport Package: 1kg/Aluminum Bag or 25kg/Drum
• Specification: 99% min
• Trademark: Puya
• Origin: China
• Production Capacity: 5000kilogram/Month

Product Description

Antiviral Powder Trifluridine CAS 70-00-8 For Anti-fection

Product Name:    Trifluridine
Synonyms:    2,4(1h,3h)-pyrimidinedione,1-(2-deoxy-beta-d-ribofuranosyl)-5-(trifluorometh;Trifluridine (Viroptic);VIROPTIC; TRIFLUOROTHYMIDINE;Triflurdine (Viroptic);2'-deoxy-5-(trifluoromethyl)-uridin;5-(trifluoromethyl)deoxyuridine;5-trifluoro-2'-deoxythymidine;alpha,alpha,alpha-trifluoro-thymidin
CAS:    70-00-8
MF:    C10H11F3N2O5
MW:    296.2
EINECS:    200-722-8
Product Categories:    PARSOL;Antivirals for Research and Experimental Use;Biochemistry;Chemical Reagents for Pharmacology Research;Nucleosides and their analogs;Nucleosides, Nucleotides & Related Reagents;Pharmaceutical Raw Materials;Pyrimidine series;API intermediates;Nucleotides and Nucleosides;Bases & Related Reagents;Nucleotides
Mol File:    70-00-8.mol

Trifluridine (trifluorothymidine, TFT), a fluorinated pyrimidine nucleoside, is an anti-herpesvirus agent and an antitumor antimetabolite agent. It is an analog of thymidine which inhibits thymidylate synthase possesses antiviral and anticancer activity. After phosphorylation by thymidine kinase, it is incorporated into DNA where it induces DNA-damage and interferes with repair enzymes. Enhances frame shift insertion and deletion in CRISPR genome editing in pluripotent stem cells.


Trifluridine CAS 70-00-8 of Chemical Properties
Melting point     190-193 °C (lit.)
density     1.4365 (estimate)
refractive index     50 ° (C=1, H2O)
storage temp.     2-8°C
solubility     Soluble in DMSO (up to 25 mg/ml) or in Water (up to 14 mg/ml)
form     solid
pka    pKa 7.85 (Uncertain)
color     Off-white
Merck     14,9687
Stability:    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 1 month.
CAS DataBase Reference    70-00-8(CAS DataBase Reference)

Function and Application of Trifluridine CAS 70-00-8
1. Trifluridine is used as anti-herpesvirus antiviral agent in ophthalmie preparations.
2. Trifluridine is also used as an anti-cancer nucleoside, mainly for the treatment of colorectal cancer, especially for the early treatment of colon cancer patients. Trimethoprim interacts directly with the DNA of the cancer, preventing the DNA from functioning properly.
3. Trifluridine ia a broad-spectrum antiviral drug, inhibits herpes simplex virus, adenovirus, herpes zoster virus, HSV-I, HSV-II, CMV, varicella virus and some adenoviruses.
4. Trafluridine is mainly used for herpes virus causing conjunctivitis, keratitis and other herpetic eye diseases. It is more effective than iodoside. It is commonly used in patients who have failed to respond to cytarabine treatment.


Packing And Shipping
1.Preferentially DHL, FedEX or TNT for quantity less than 50kg, air shipping for 100kg above, sea shipping for quantity over 500kg.
2.For customers from Russia,Mexico,Turkey,Solvenia,Romania,etc,before placing an order,please kindly confirm if you can make clearance when goods reach your customs.

Shipping Terms
By Express	By Air	By Sea
Suitable for under 50kg Fast:3-4 days High cost Door to door service Easy to pick up the goods	Suitable for more than 50kg Fast:3-4 days High cost Airport to airport Professional broker needed	Suitable for more than 500kg Slow:15-30 days Low cost Port to port Professional broker needed

 

Company Profile
Anhui puya biological technology co.,ltd was established in Hefei. Registered capital is 5 million. It is specialized in manufacture plant extract, API and chemicals raw material powder, food additives and oil. which are applied to skin care, healthcare, weight loss products, sex improvement, and pharmaceuticals. We will uphold honesty and pragmatic, innovative and enterprising service purposes, and provide a variety of quality services to our customers at abroad. It aims at supplying good product and comfort service. The strict quality control is to meet the customer's requirement, to get a highly praised and to be high quality supplier. If you have any question, or need samples, please feel free to contact us.

FAQ
Q1. What's the MOQ?
A: Usually 1 kg.  It is based on the different product. Some are 1g and some are 1 ton. Please be free to consult our salesman.
 
Q2. What's the shipping time?
A: If in stock, we will ship it out immediately.  By FedEx will be 3~5 days to you.
 
Q3. If I need less than the MOQ, is it possible?
A: Yes. Please be free to consult our salesman.
 
Q4. Can you supply the free sample?
A: Usually it is possible. but the shipping cost be paid by customers. It based on the different product. Please be free to consult our salesman.
 
Q5. How to store the product?
A: Store in cool and dry place. It must be in well closed containers. The shelf life will be 2 years.
 
Q6: What's your main payment method?
A: T/T, trade assurance, west union, money gram.
 
Q7: Do you have COA, MSDS, CO, Health certificate, form 9 or other certificate?
A: Yes, we have. pls be free to contact us to get updated one.