Good Quality Milrinone Lactate CAS 100286-97-3

• CAS No.: 100286-97-3
• Formula: C12h9n3o
• EINECS: /
• Type: Pharmaceutical
• Appearance: Powder
• Quality: Top
• Model NO.: py0706
• Colour: White
• Grade: Pharmaceutical
• MOQ: 1kg
• Package: Carton
• Shipping: FedEx
• Transport Package: 25kg/Drum
• Specification: 99%
• Trademark: puya
• Origin: China
• Production Capacity: 10ton/Year

Product Description

Milrinone Lactate CAS 100286-97-3

Product Name	Milrinone lactate
CAS	100286-97-3
Appearance	White powder
Molecular formula	C12H9N3O
Molecular Weight	N/A
Assay	99%
Shelf Life	24 months when properly stored
Storage	Keep in a cool, dry, dark location

Milrinone, is a medication used in patients who have heart failure. It is a phosphodiesterase 3 inhibitor that works to increase the heart's contractility and decrease pulmonary vascular resistance. Milrinone also works to vasodilate which helps alleviate increased pressures (afterload) on the heart, thus improving its pumping action. While it has been used in people with heart failure for many years, recent studies suggest that milrinone may exhibit some negative side effects that have caused some debate about its use clinically.

Specification

Appearance	White off-white crystalline powder	Conforms
Identification	IR, HPLC	Conforms
Water	1.00%	0.30%
Residue on ignition	0.10%	0.02%
Sulphate	0.02%	Conforms
Chloride	0.05%	Conforms
Ethyl ace tate	0.30%	0.12%
Heavy metals	20ppm	Conforms
Related substances	Total impurity 1.0%	0.88%
	Any impurity 0.5%	0.17%
Assay	98.00%	99.12%

Function
Overall, milrinone supports ventricular functioning of the heart by decreasing the degradation of cAMP and
thus increasing phosphorylation levels of many components in the heart that contribute to contractility and
heart rate. Milrinone use following cardiac surgery has been under some debate because of the potential
increase risk of postoperative atrial arrhythmias. However, in the short term milrinone has been deemed
beneficial to those experiencing heart failure and an effective therapy to maintain heart function following
cardiac surgeries. There is no evidence of any long term beneficial effects on survival.