Puya Supply High Quality Amifostine CAS 20537-88-6 Use for Radiotherapy Protective Agents

• CAS No.: 20537-88-6
• Formula: C5h15n2o3PS
• EINECS: 633-786-4
• Type: Pharmaceutical Intermediates
• Appearance: Powder
• Quality: Refined
• Model NO.: PY20221025
• Colour: White
• Transport Package: 1kg/Aluminum Bag or 25kg/Drum
• Specification: 99% min
• Trademark: Puya
• Origin: China
• Production Capacity: 5000kilogram/Month

Product Description

Puya Supply High Quality Amifostine CAS 20537-88-6 Use For Radiotherapy Protective Agents

Product Name:    Amifostine
Synonyms:    Ethyol;γphos;Fosteamine;2-(3-Aminopropyl)aminoethyl phosphorothioate, WR2721;Ethiotas;S-2-[(3-Aminopropyl)amino]ethanethi ol dihydrogen phosphate ester;Amifostine,2-(3-Aminopropyl)aminoethyl phosphorothioate, WR2721;AMifostine anhydrous
CAS:    20537-88-6
MF:    C5H15N2O3PS
MW:    214.22
EINECS:    633-786-4
Product Categories:    Active Pharmaceutical Ingredients;Radioprotective Agent;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Seleni um Compounds;TIAPRIDAL
Mol File:    20537-88-6.mol

Amifostine, an organic thiophosphate, was introduced for the reduction of cisplatin-induced renal toxicity in patients with advanced ovarian cancer. It is also a radio-protective agent. Amifostine is a prodrug which is rapidly dephosphorylated, preferentially in non-tumor tissues to the active thiol. This agent binds to chemotherapeutic drugs and free radicals released by radiotherapy. The protective effect of amifostine was observed in a wide range of normal organs including bone marrow and gastrointestinal mucosa without interfering with the anti-tumor effect of chemohadiotherapy, indicating an increased therapeutic index for existing cancer treatment. Amifostine is also being evaluated as a cytoprotective in other types of tumors including lung, breast, head and neck cancers. It was reported to be a potent mucolytic with potential in cystic fibrosis.

Amifostine CAS 20537-88-6 of Chemical Properties
Melting point     160-1610C
Boiling point     441.7±51.0 °C(Predicted)
density     1.367±0.06 g/cm3(Predicted)
storage temp.     2-8°C
solubility     Soluble in Water.
pka    1.28±0.10(Predicted)
form     powder
color     White
Stability:    Stable for 1 year from date of purchase as supplied. Solutions in distilled water may be stored at -20° for up to 3 months.
CAS DataBase Reference    20537-88-6(CAS DataBase Reference)

Function and Application of Amifostine CAS 20537-88-6
1. Chemotherapeutic cytoprotective agents and radiotherapy protectants that selectively protect normal tissue cells during radiotherapy or chemotherapy when killing cancer cells, allowing patients to receive continuous therapies. It is used to relieve the nephrotoxicity of anticancer drugs, and is effective in preventing toxic side effects such as haematopoietic and immune damage caused by radiotherapy, and is also used to reduce infections associated with neutropenia.
2. Amifostine is a normal cell protector and is mainly used for the adjuvant treatment of various cancers. Its application prior to chemotherapy for patients with a variety of cancers including lung, ovarian, breast, nasopharyngeal, bone, gastrointestinal and haematological tumours significantly reduces the toxicity of the kidney, bone marrow, heart, ear and nervous system produced by the chemotherapeutic drugs without reducing their efficacy. The use of this product prior to radiotherapy significantly reduces the incidence of oral dryness and mucositis.


Packing And Shipping
1.Preferentially DHL, FedEX or TNT for quantity less than 50kg, air shipping for 100kg above, sea shipping for quantity over 500kg.
2.For customers from Russia,Mexico,Turkey,Solvenia,Romania,etc,before placing an order,please kindly confirm if you can make clearance when goods reach your customs.

Shipping Terms
By Express	By Air	By Sea
Suitable for under 50kg Fast:3-4 days High cost Door to door service Easy to pick up the goods	Suitable for more than 50kg Fast:3-4 days High cost Airport to airport Professional broker needed	Suitable for more than 500kg Slow:15-30 days Low cost Port to port Professional broker needed

 

Company Profile
Anhui puya biological technology co.,ltd was established in Hefei. Registered capital is 5 million. It is specialized in manufacture plant extract, API and chemicals raw material powder, food additives and oil. which are applied to skin care, healthcare, weight loss products, sex improvement, and pharmaceuticals. We will uphold honesty and pragmatic, innovative and enterprising service purposes, and provide a variety of quality services to our customers at abroad. It aims at supplying good product and comfort service. The strict quality control is to meet the customer's requirement, to get a highly praised and to be high quality supplier. If you have any question, or need samples, please feel free to contact us.

FAQ
Q1. What's the MOQ?
A: Usually 1 kg.  It is based on the different product. Some are 1g and some are 1 ton. Please be free to consult our salesman.
 
Q2. What's the shipping time?
A: If in stock, we will ship it out immediately.  By FedEx will be 3~5 days to you.
 
Q3. If I need less than the MOQ, is it possible?
A: Yes. Please be free to consult our salesman.
 
Q4. Can you supply the free sample?
A: Usually it is possible. but the shipping cost be paid by customers. It based on the different product. Please be free to consult our salesman.
 
Q5. How to store the product?
A: Store in cool and dry place. It must be in well closed containers. The shelf life will be 2 years.
 
Q6: What's your main payment method?
A: T/T, trade assurance, west union, money gram.
 
Q7: Do you have COA, MSDS, CO, Health certificate, form 9 or other certificate?
A: Yes, we have. pls be free to contact us to get updated one.