Hot Sale Tranilast CAS 53902-12-8 Use for Bronchial Asthma

• CAS No.: 53902-12-8
• Formula: C18h17no5
• EINECS: /
• Type: Pharmaceutical Intermediates
• Appearance: Powder
• Quality: Refined
• Model NO.: PY202303021346
• Colour: White
• Transport Package: 1kg/Aluminum Bag or 25kg/Drum
• Specification: 99% min
• Trademark: Puya
• Origin: China
• Production Capacity: 5000kilogram/Month

Product Description

Hot Sale Tranilast CAS 53902-12-8 Use For Bronchial Asthma

Product Name:    Tranilast
Synonyms:    2-((3-(3,4-dimethoxyphenyl)-1-oxo-2-propenyl)amino)-benzoicaci;n-(3,4-dimethoxycinnamoyl)-anthranilicaci;n-5';rizaben;SB-252218;N-(3',4'-DIMETHOXYCINNAMOYL)ANTHRANILIC A CID;Tranilast - CAS 53902-12-8 - Calbiochem;2-[[3-(3,4-DIMETHOXYPHENYL)-1-OXO-2-PROPENYL]AMINO] BENZOIC ACID
CAS:    53902-12-8
MF:    C18H17NO5
MW:    327.33
EINECS:    
Product Categories:    PEXID;Inhibitors;Angiogenesis and Metastasis;Amines;Aromatics;Intermediates & Fine Chemicals;Angiotensin;Pharmaceuticals
Mol File:    53902-12-8.mol

Tranilast is a drug that is used for various medical conditions such as bronchial asthma, allergic rhinitis, keloids, hypertrophic scars, and diabetic nephropathy. It works by inhibiting the release of inflammatory mediators, such as histamine and leukotrienes, which are involved in allergic and inflammatory responses.

Tranilast is classified as an anti-inflammatory and anti-allergic agent, and it is believed to have additional properties that could make it useful for treating various other medical conditions. For example, some studies suggest that it may have anti-cancer properties, although more research is needed to confirm this.

Tranilast CAS 53902-12-8 of Chemical Properties
Melting point     166.2-168.2 °C (lit.)
Boiling point     465.23°C (rough estimate)
density     1.3185 (rough estimate)
refractive index     1.5100 (estimate)
storage temp.     2-8°C
solubility     DMSO: 18 mg/mL
form     powder
pka    3.47±0.36(Predicted)
color     white to beige
Merck     14,9570
Stability:    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
InChIKey    NZHGWWWHIYHZNX-CSKARUKUSA-N
CAS DataBase Reference    53902-12-8(CAS DataBase Reference)

Function and Application of Tranilast CAS 53902-12-8

1.  Antiallergic drug, used to treat bronchial asthma, allergic rhinitis and atopic dermatitis.
2. coronary vasodilator
3.Tranilast is a compound that exhibits anti-inflammatory and immunomodulatory effects by inhibiting lipid mediator and cytokine release from inflammatory cells and interfering with PDGF- and TGF-β1-induced proliferation and migration of vascular medial smooth muscle cells. Tranilast suppresses production of prostaglandin D2 (IC50 = 0.1 mM), prostaglandin E2 (IC50 = ~1-20 μM), thromboxane B2 (IC50 = ~10-50 μM), TGF-β1 (IC50 = ~100-200 μM), and interleukin-8 (IC50 = ~100 μM) in in vitro models as well as attenuates of the proinflammatory activity of human monocytes. While originally marketed as an antiallergenic drug, the efficacy of tranilast in preventing restenosis after percutaneous coronary intervention has been tested in a large-scale clinical trial. Additionally, tranilast inhibits VEGF-induced angiogenetic activities (i.e., proliferation, migration and tube formation of vascular endothelial cells) with IC50 values of 22, 18 and 193 μM, which may prove therapeutic for various retinal diseases.[Cayman Chemical]

Packing And Shipping
1.Preferentially DHL, FedEX or TNT for quantity less than 50kg, air shipping for 100kg above, sea shipping for quantity over 500kg.
2.For customers from Russia,Mexico,Turkey,Solvenia,Romania,etc,before placing an order,please kindly confirm if you can make clearance when goods reach your customs.

Shipping Terms
By Express	By Air	By Sea
Suitable for under 50kg Fast:3-4 days High cost Door to door service Easy to pick up the goods	Suitable for more than 50kg Fast:3-4 days High cost Airport to airport Professional broker needed	Suitable for more than 500kg Slow:15-30 days Low cost Port to port Professional broker needed

 

Company Profile
Anhui puya biological technology co.,ltd was established in Hefei. Registered capital is 5 million. It is specialized in manufacture plant extract, API and chemicals raw material powder, food additives and oil. which are applied to skin care, healthcare, weight loss products, sex improvement, and pharmaceuticals. We will uphold honesty and pragmatic, innovative and enterprising service purposes, and provide a variety of quality services to our customers at abroad. It aims at supplying good product and comfort service. The strict quality control is to meet the customer's requirement, to get a highly praised and to be high quality supplier. If you have any question, or need samples, please feel free to contact us.

FAQ
Q1. What's the MOQ?
A: Usually 1 kg.  It is based on the different product. Some are 1g and some are 1 ton. Please be free to consult our salesman.
 
Q2. What's the shipping time?
A: If in stock, we will ship it out immediately.  By FedEx will be 3~5 days to you.
 
Q3. If I need less than the MOQ, is it possible?
A: Yes. Please be free to consult our salesman.
 
Q4. Can you supply the free sample?
A: Usually it is possible. but the shipping cost be paid by customers. It based on the different product. Please be free to consult our salesman.
 
Q5. How to store the product?
A: Store in cool and dry place. It must be in well closed containers. The shelf life will be 2 years.
 
Q6: What's your main payment method?
A: T/T, trade assurance, west union, money gram.
 
Q7: Do you have COA, MSDS, CO, Health certificate, form 9 or other certificate?
A: Yes, we have. pls be free to contact us to get updated one.