Niacinamide/ Nicotinamide CAS 98-92-0
Type: Vitamins
Origin: China
CAS No.: 98-92-0
AUCO No.: 830
Packing: 25kg drum/25kg carton
Nicotinamide, also known as nicotinamide, is an amide compound of niacin. White crystalline powder; odorless or almost odorless, bitter in taste; slightly hygroscopic. The relative density is 1.4, and the melting point is 129-131 °C. 1g of this product is soluble in 1mL water, 1.5mL ethanol or 10mL glycerol, but insoluble in ether. The pH of a 10% aqueous solution is 6.5-7.5. It is relatively stable, resistant to acid, alkali and high temperature. It is stable to light and heat in dry air, and generates niacin when heated in alkaline or acidic solution.
Specification
| Items |
Standard |
| Identification |
The IR Absorption spectrum is concordant with the spectrum of reference standard. |
| Test A (IR) |
Ratio:A245/A262,between 0.63 and 0.67 |
| Test B (UV) |
0.63-0.67 |
| Assay(By HPLC) |
Not less than 98.5% W/W and not more than 101.5%W/W of C6H6N2O, calculated on the dried basis. |
| Characteristics |
White crystalline powder |
| Melting range |
128ºC-131ºC |
| Loss on drying |
≤0.5% |
| Residue on ignition |
≤0.1% |
| Heavy metals |
≤0.003% |
| Items |
Specification |
| Identification |
Complies |
| Assay (HPLC, %) |
98.5-101.5 |
| Appearance |
white crystalline powder |
| Melting range (ºC) |
128-131 |
| Loss on drying (%) |
0.5max |
| Residue on ignition (%) |
0.1max |
| Heavy metals (%) |
0.003max |
| Readily carbonizable substances |
Test as per FCCIV/ USP37 |
| Organic volatile impurities |
Test as per FCCIV/ USP37 |
| Residual solvents |
Test as per FCCIV/ USP37 |
Function
1. Niacinamide can interfere with the transport of melanin, restrict melanin in melanocytes, prevent melanocytes from continuing to produce melanin, and at the same time prevent melanin from being transmitted to the skin surface to darken the skin, thereby achieving a whitening effect.
2. Niacinamide has been proven to have a good anti-glycation effect, and the substance produced by skin glycation is brown, which will make the skin look dark. The anti-glycation of niacinamide helps to whiten the skin, thereby brightening the complexion.
Application
Nicotinamide is mainly used in the medical cosmetic industry.
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