Hot Sale Gemcitabi Ne HCl CAS 122111-03-9 for Anti Tumour

• CAS No.: 122111-03-9
• Formula: C9h12clf2n3o4
• EINECS: 601-823-3
• Type: Pharmaceutical Intermediates
• Appearance: Powder
• Quality: Refined
• Model NO.: PY202210141613
• Colour: White
• Transport Package: 1kg/Aluminum Bag or 25kg/Drum
• Specification: 99% min
• Trademark: Puya
• Origin: China
• Production Capacity: 5000kilogram/Month

Product Description

Hot Sale Gemcitabi ne Hcl CAS 122111-03-9 For Anti Tumour

Product Name:    Gemcitabi ne hydrochloride
Synonyms:    2',2'-difluorodeoxycytidinemonohydrochloride;2'-deoxy-2',2'-difluorocytidinemonohydrochloride;2'-deoxy-2',2'-difluoro-cytidinmonohydrochloride;gemzar;ly188011;ly188011hydrochloride;2',2'-DIFLUORO-2'-DEOXYCYTIDINE;2'-DEOXY-2',2'-DIFLUOROCYTIDINE
CAS:    122111-03-9
MF:    C9H12ClF2N3O4
MW:    299.66
EINECS:    601-823-3
Product Categories:    Inhibitors;Anti-cancer&immunity;Bases & Related Reagents;Intermediates & Fine Chemicals;Nucleotides;Antineoplastic drug, difluorine nucleoside analog;Active Pharmaceutical Ingredients;API;Antineoplastic;Pharmaceuticals;122111-03-9
Mol File:    122111-03-9.mol


Gemcitabi ne hydrochloride is a synthetic novel difluoro nucleoside drug that is anti-metabolic and antineoplastic. It is researched and developed by the Eli Lilly and Company and approved to be listed in South Africa, Sweden, the Netherlands, Australia and other countries in 1995. The United States Food and Drug Administration ( referred FDA) approved it as the first-line therapy for the clinical treatment of non-small cell lung cancer and pancreatic cancer. The main manufacturers of gemcitabi ne hydrochloride in domestic are Jiangsu Stock hausen Pharmaceutical Co., Ltd., and Harbin, Yu Heng Pharmaceutical company.
Gemcitabi ne hydrochloride, as a pro-drug, is a good substrate for the acidification of deoxygenation of thymine kinase phosphorus in the cell, and under the action of the enzyme, it can be converted into the following metabolites: gemcitabi ne mono-phosphate (dFdCMP), gemcitabi ne diphosphate (dFdCDP) and gemcitabi ne triphosphate (dFdCTP), among which the latter two are the active products.

Gemcitabi ne Hcl CAS 122111-03-9 of Chemical Properties
Melting point     >250°C dec.
alpha     D +48°; 365 +257.9° (c = 1.0 in deuterated water)
storage temp.     2-8°C
solubility     H2O: ≥10mg/mL
form     White powder
color     White
λmax    268nm(H2O)(lit.)
Merck     14,4386
Stability:    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month.
CAS DataBase Reference    122111-03-9(CAS DataBase Reference)

Function and Application of Gemcitabi ne Hcl CAS 122111-03-9
Gemcitabi ne HCl (CAS 122111-03-9) is a chemotherapy drug that is used to treat several types of cancer, including pancreatic, lung, breast, ovarian, and bladder cancer. It works by interfering with the growth and spread of cancer cells in the body.

Gemcitabi ne HCl is a nucleoside analog that is structurally similar to deoxycytidine. It is metabolized inside cells to its active form, gemcitabi ne diphosphate, which inhibits DNA synthesis and causes cell death. Gemcitabi ne HCl is usually administered by injection into a vein.

Gemcitabi ne HCl has several applications in the treatment of cancer, including:

Pancreatic Cancer: Gemcitabi ne HCl is often used as the first-line treatment for advanced pancreatic cancer. It has been shown to improve survival and quality of life in patients with this disease.

Lung Cancer: Gemcitabi ne HCl is used in combination with other chemotherapy drugs to treat non-small cell lung cancer. It can also be used as a single agent for the treatment of small cell lung cancer.

Breast Cancer: Gemcitabi ne HCl can be used to treat metastatic breast cancer that has not responded to other chemotherapy drugs.

Ovarian Cancer: Gemcitabi ne HCl is used in combination with other chemotherapy drugs to treat ovarian cancer that has returned after initial treatment.

Bladder Cancer: Gemcitabi ne HCl is used in combination with other chemotherapy drugs to treat advanced bladder cancer.

Packing And Shipping
1.Preferentially DHL, FedEX or TNT for quantity less than 50kg, air shipping for 100kg above, sea shipping for quantity over 500kg.
2.For customers from Russia,Mexico,Turkey,Solvenia,Romania,etc,before placing an order,please kindly confirm if you can make clearance when goods reach your customs.

Shipping Terms
By Express	By Air	By Sea
Suitable for under 50kg Fast:3-4 days High cost Door to door service Easy to pick up the goods	Suitable for more than 50kg Fast:3-4 days High cost Airport to airport Professional broker needed	Suitable for more than 500kg Slow:15-30 days Low cost Port to port Professional broker needed

 

Company Profile
Anhui puya biological technology co.,ltd was established in Hefei. Registered capital is 5 million. It is specialized in manufacture plant extract, API and chemicals raw material powder, food additives and oil. which are applied to skin care, healthcare, weight loss products, sex improvement, and pharmaceuticals. We will uphold honesty and pragmatic, innovative and enterprising service purposes, and provide a variety of quality services to our customers at abroad. It aims at supplying good product and comfort service. The strict quality control is to meet the customer's requirement, to get a highly praised and to be high quality supplier. If you have any question, or need samples, please feel free to contact us.

FAQ
Q1. What's the MOQ?
A: Usually 1 kg.  It is based on the different product. Some are 1g and some are 1 ton. Please be free to consult our salesman.
 
Q2. What's the shipping time?
A: If in stock, we will ship it out immediately.  By FedEx will be 3~5 days to you.
 
Q3. If I need less than the MOQ, is it possible?
A: Yes. Please be free to consult our salesman.
 
Q4. Can you supply the free sample?
A: Usually it is possible. but the shipping cost be paid by customers. It based on the different product. Please be free to consult our salesman.
 
Q5. How to store the product?
A: Store in cool and dry place. It must be in well closed containers. The shelf life will be 2 years.
 
Q6: What's your main payment method?
A: T/T, trade assurance, west union, money gram.
 
Q7: Do you have COA, MSDS, CO, Health certificate, form 9 or other certificate?
A: Yes, we have. pls be free to contact us to get updated one.