CAS 943-73-7 L-Homophenylalanine; (S) -Alpha-Amino-Benzenebutanoic Acid

• CAS No.: 943-73-7
• Formula: C10h13no2
• EINECS: 213-403-3
• Color: White
• Appearance: Powder
• Grade: Food and Pharm
• Model NO.: py0585
• MOQ: 1kg
• Package: Carton
• Shipping: FedEx
• Transport Package: Puya
• Specification: 99%
• Trademark: puya
• Origin: China
• Production Capacity: 10ton/Year

Product Description

CAS 943-73-7 L-Homophenylalanine

Product Name	L-Homophenylalanine
CAS No.	943-73-7
Appearance	White crystalline powder
Assay	≥99%
Capacity	20mt/year
Min.packing	100gram
Application	Organic intermediate
Standard	Enterprise export
Manufacturer	Jinan Finer Chemical Co., Ltd
More information	Synonyms: (S)-alpha-Amino-benzenebutanoic acid                    (+)-2-Amino-4-phenylbutyric acid Molecular Formula: C10H13NO2 Molecular Weight: 179.22 CAS Registry Number: 943-73-7 EINECS: 213-403-3 Melting point: 300 ºC alpha: 45 º (C=1, 3N HCl 19 ºC)

Specification

DESCRIPTION	white or off-white crystalline powder, insoluble in water
	Molecular formula	2-(s)-amino-4-phenylbutanoic acid
	Structural Formula
	Formula Weight	179.22
SPECIFICATION (FCCIV,1996)	Optical Purity	>=99.0%(e.e% CHIRAL HPLC)
	Chemical Purity	>=98.0%
	Specific Rotation	+45.0~ +45.8(c=1.0,1N HCl)
	Heavy Metals[as Pb]	<=20mg/kg
	Arsenic[as As]	<=3mg/kg
	Loss on Drying (105 4hr)	<=0.5%
Main Function and Purpose	L-homophenlyalaine is a kind of chiral unnatural -amino acid. This kind of amino acid and its ester are widely used in manufacturing pharmaceuticals and pesticides. It is a very important intermediate for the synthesis of drugs such as ACE(Angiotension Converting Enzyme) Inhibitor and CHF(Congestive Heartfailure).  Both Physiologic Investigation and clinical trial testified that ACE Inhibitor has been regarded as the landmark in the history of cardiovascular drugs. Owing to its excellent clinical curative effect and good tolerance, it has been firstly chosen to manufacture drugs for hypertension such as Captopril, Enalapril, Benazepri. These drugs are in top ten list in the world. Among the 19 types of ACE inhibitors, 12 types contain chiral unnatural amino acid, L-homophenlyalanine.  L-homophenlyalanine is also an important chiral intermediate to synthesize -lactam antibiotics, acetylcholinesterase inhibitor and neutral endopeptidase(NEP) inhibitor.