| CAS No.: | 69004-04-2 |
|---|---|
| Formula: | C18h14f3n3o6s |
| EINECS: | 629-740-8 |
| Type: | Pharmaceutical Intermediates |
| Appearance: | Powder |
| Quality: | Refined |
| Customization: |
|---|
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Audited Supplier Hot Sale Ponazuril CAS 69004-04-2 For Anticocciditis
Product Name: Ponazuril
Synonyms: Toltrazuril sulfone Ponazuril;1-Methyl-3-{3-methyl-4-[4-(trifluoromethylsulfonyl)phenoxy]phenyl}-1,3,5-triazine-2,4,6(1H,3H;Ponazuril;ToltrazurilSulfone;1-Methyl-3-{3-methyl-4-[4-(trifluoromethylsulfonyl)phenoxy]phenyl}-1,3,5-triazine-2,4,6(1H,3H,5H)-trione;Ponazuril [inn];Unii-jpw84as66u;1-methyl-3-[3-methyl-4-[4-(trifluoromethylsulfonyl)phenoxy]phenyl]-1,3,5-triazinane-2,4,6-trione
CAS: 69004-04-2
MF: C18H14F3N3O6S
MW: 457.38
EINECS: 629-740-8
Product Categories: Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File: 69004-04-2.mol
Toltrazuril sulfone is an active metabolite of the coccidiostat toltrazuril . Toltrazuril sulfone is formed from toltrazuril via the intermediate metabolite toltrazuril sulfoxide by cytochrome P450 (CYP) enzymes, including CYP3A. It inhibits T. gondii tachyzoite production in African green monkey kidney cells when used at concentrations of 0.1, 1, and 5 μg/ml. Toltrazuril sulfone completely prevents infection with T. gondii tachyzoites in a mouse model of fatal toxoplasmosis when administered at doses of 10 or 20 mg/kg one day prior to, and daily for 10 days following, infection. It also reduces the number of infected mice in the same model when administered at a dose of 10 mg/kg for 11 days starting six days following infection. Formulations containing toltrazuril sulfone have been used in the treatment of equine protozoal myeloencephalitis (EPM) in horses.
Ponazuril CAS 69004-04-2 of Chemical Properties
Melting point 242°
density 1.507±0.06 g/cm3(Predicted)
storage temp. Refrigerator
solubility Acetontrile (Slightly), DMSO (Slightly), Methan ol (Slightly)
pka 6.46±0.20(Predicted)
form neat
color White to Off-White
InChIKey VBUNOIXRZNJNAD-UHFFFAOYSA-N
CAS DataBase Reference 69004-04-2
Function and Application of Ponazuril CAS 69004-04-2
Ponazuril (CAS 69004-04-2) is a veterinary drug used to treat protozoan infections, particularly coccidiosis in dogs and horses. It belongs to the triazine class of compounds and works by inhibiting the energy metabolism of the protozoa, leading to their death.
The drug is administered orally and is available in a suspension form for easy dosing. It has a long half-life, allowing for less frequent dosing and better treatment compliance.
Ponazuril is particularly effective against coccidia parasites, which can cause severe diarrhea, dehydration, weight loss, and even death in infected animals. It is also used to treat other protozoan infections, such as toxoplasmosis and neosporosis.
Ponazuril is considered safe for use in animals, with mild side effects such as lethargy, anorexia, and diarrhea being reported in some cases. However, it is important to use the drug only under veterinary supervision, as incorrect dosing or administration can lead to adverse effects.
In summary, ponazuril is a veterinary drug used to treat protozoan infections, particularly coccidiosis, in dogs and horses. It is administered orally and has a long half-life, making it effective and easy to use.
| Shipping Terms | ||
| By Express | By Air | By Sea |
| Suitable for under 50kg Fast:3-4 days High cost Door to door service Easy to pick up the goods |
Suitable for more than 50kg Fast:3-4 days High cost Airport to airport Professional broker needed |
Suitable for more than 500kg Slow:15-30 days Low cost Port to port Professional broker needed |
Company Profile
Anhui puya biological technology co.,ltd was established in Hefei. Registered capital is 5 million. It is specialized in manufacture plant extract, API and chemicals raw material powder, food additives and oil. which are applied to skin care, healthcare, weight loss products, sex improvement, and pharmaceuticals. We will uphold honesty and pragmatic, innovative and enterprising service purposes, and provide a variety of quality services to our customers at abroad. It aims at supplying good product and comfort service. The strict quality control is to meet the customer's requirement, to get a highly praised and to be high quality supplier. If you have any question, or need samples, please feel free to contact us.
FAQ
Q1. What's the MOQ?
A: Usually 1 kg. It is based on the different product. Some are 1g and some are 1 ton. Please be free to consult our salesman.
Q2. What's the shipping time?
A: If in stock, we will ship it out immediately. By FedEx will be 3~5 days to you.
Q3. If I need less than the MOQ, is it possible?
A: Yes. Please be free to consult our salesman.
Q4. Can you supply the free sample?
A: Usually it is possible. but the shipping cost be paid by customers. It based on the different product. Please be free to consult our salesman.
Q5. How to store the product?
A: Store in cool and dry place. It must be in well closed containers. The shelf life will be 2 years.
Q6: What's your main payment method?
A: T/T, trade assurance, west union, money gram.
Q7: Do you have COA, MSDS, CO, Health certificate, form 9 or other certificate?
A: Yes, we have. pls be free to contact us to get updated one.
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