• High Quality Miconazo Le Nitrate CAS 22832-87-7 for Anti Fungus
  • High Quality Miconazo Le Nitrate CAS 22832-87-7 for Anti Fungus
  • High Quality Miconazo Le Nitrate CAS 22832-87-7 for Anti Fungus
  • High Quality Miconazo Le Nitrate CAS 22832-87-7 for Anti Fungus
  • High Quality Miconazo Le Nitrate CAS 22832-87-7 for Anti Fungus
  • High Quality Miconazo Le Nitrate CAS 22832-87-7 for Anti Fungus

High Quality Miconazo Le Nitrate CAS 22832-87-7 for Anti Fungus

CAS No.: 22832-87-7
Formula: C18h15cl4n3o4
EINECS: 245-256-6
Type: Pharmaceutical Intermediates
Appearance: Powder
Quality: Refined
Samples:
US$ 100/Piece 1 Piece(Min.Order)
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Customization:
Gold Member Since 2022

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Anhui, China
Importers and Exporters
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More than 50% of buyers repeatedly choose the supplier
In-stock Capacity
The supplier has In-stock capacity
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Basic Info.

Model NO.
PY202210141704
Colour
White
Grade
Pharm
Spec.
USP, Ep, Cp
MOQ
1kg
Shipping Time
After Payment
Transport Package
1kg/Aluminum Bag or 25kg/Drum
Specification
99% min
Trademark
Puya
Origin
China
Production Capacity
5000kilogram/Month

Product Description

High Quality Miconazo le Nitrate CAS 22832-87-7 For Anti Fungus

Product Name:    Miconazo le nitrate
Synonyms:    Isoconazole IMpurity C Nitrate (Miconazo le Nitrate);1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole,nitrate (1:1);NSC 169434 Nitrate;1H-Imidazole, 1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-, nitrate (1:1);()-MICONAZO LE NITRATE SALT, IMIDAZO;1-(2,4-Dichloro-β-[(2,4-dichlorobenzyl)oxy]phenethyl)imidazole 1-[2-(2,4-Dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole Nitrate;monistat;MICONAZO LE NITRATE USP
CAS:    22832-87-7
MF:    C18H15Cl4N3O4
MW:    479.14
EINECS:    245-256-6
Product Categories:    MONISTAT;API;Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Active Pharmaceutical Ingredients;Organics;Antifungals for Research and Experimental Use;Biochemistry;API's;Antifungal;22832-87-7
Mol File:    22832-87-7.mol



Miconazo le nitrate is a kind of artificially synthetic 1-phenylethyl imidazole derivatives and belongs to imidazole-class broad-spectrum antifungal drug. It is a commonly used drug for treating skin ringworm without containing hormones and without side effects. Its main active ingredient is miconazo le. However, miconazo le nitrate is now seldom used in China. Its antibacterial spectrum, antibacterial activity and mechanism of action are all similar with clotrimazole. It can be used as a substitute drug when the treatment of amphotericin in deep fungal infection is invalid. It is suitable for treating the systemic, disseminated infection caused by some kinds of fungus such as Cryptococcus neoformans and Candida albicans. The efficacy of absorption via oral administration is poor. After topical administration, the drug is mainly maintained in the lesion place with only a small fraction getting absorbed into the body. In vivo, it is widely distributed in various body tissues and fluids and can penetrate into the inflamed joints, vitreous and the peritoneum, but the concentration in the sputum and saliva is low and it has a poor penetrating capability through the blood-brain barrier and is difficult to penetrate through the blood-brain barrier. It has a plasma protein binding rate of 90%. It is mainly inactive through liver metabolism into inactive metabolites with 14%~22% of the metabolites being excreted through urine, of which less than 1% of drug being in its prototype.

Miconazo le Nitrate CAS 22832-87-7 of Chemical Properties
Melting point     170-185 C
density     1.5000 (rough estimate)
refractive index     1.6200 (estimate)
storage temp.     2-8°C
solubility     pyridi ne: soluble50mg/mL
form     neat
color     white to off-white
optical activity    [α]25/D 0°, c = 10 in water
Water Solubility     Slightly soluble in water. Soluble in propyle ne glycol or pyridi ne.
Merck     14,6178
InChIKey    MCCACAIVAXEFAL-UHFFFAOYSA-N
CAS DataBase Reference    22832-87-7(CAS DataBase Reference)

Function and Application of Miconazo le Nitrate CAS 22832-87-7
1. Antifungal (topical).
2. An antifungal agent that inhibits platelet cyclooxygenase
3. Miconazo le is a widely used antifungal imidazole that acts by inhibiting the 14α-demethylation of lanosterol, which consequently leads to the inhibition of ergosterol synthesis in fungal cell membranes. Additionally, miconazol e has been shown to induce reactive oxygen species in fungal biofilms, demonstrating a MIC value of ≥256 μM against Candida spp.

High Quality Miconazo Le Nitrate CAS 22832-87-7 for Anti FungusHigh Quality Miconazo Le Nitrate CAS 22832-87-7 for Anti Fungus
Packing And Shipping
1.Preferentially DHL, FedEX or TNT for quantity less than 50kg, air shipping for 100kg above, sea shipping for quantity over 500kg.
2.For customers from Russia,Mexico,Turkey,Solvenia,Romania,etc,before placing an order,please kindly confirm if you can make clearance when goods reach your customs.
Shipping Terms
By Express By Air By Sea
Suitable for under 50kg
Fast:3-4 days
High cost
Door to door service
Easy to pick up the goods
Suitable for more than 50kg
Fast:3-4 days
High cost
Airport to airport
Professional broker needed
Suitable for more than 500kg
Slow:15-30 days
Low cost
Port to port
Professional broker needed

High Quality Miconazo Le Nitrate CAS 22832-87-7 for Anti Fungus
 

High Quality Miconazo Le Nitrate CAS 22832-87-7 for Anti Fungus
Company Profile
Anhui puya biological technology co.,ltd was established in Hefei. Registered capital is 5 million. It is specialized in manufacture plant extract, API and chemicals raw material powder, food additives and oil. which are applied to skin care, healthcare, weight loss products, sex improvement, and pharmaceuticals. We will uphold honesty and pragmatic, innovative and enterprising service purposes, and provide a variety of quality services to our customers at abroad. It aims at supplying good product and comfort service. The strict quality control is to meet the customer's requirement, to get a highly praised and to be high quality supplier. If you have any question, or need samples, please feel free to contact us.
High Quality Miconazo Le Nitrate CAS 22832-87-7 for Anti Fungus

FAQ
Q1. What's the MOQ?
A: Usually 1 kg.  It is based on the different product. Some are 1g and some are 1 ton. Please be free to consult our salesman.
 
Q2. What's the shipping time?
A: If in stock, we will ship it out immediately.  By FedEx will be 3~5 days to you.
 
Q3. If I need less than the MOQ, is it possible?
A: Yes. Please be free to consult our salesman.
 
Q4. Can you supply the free sample?
A: Usually it is possible. but the shipping cost be paid by customers. It based on the different product. Please be free to consult our salesman.
 
Q5. How to store the product?
A: Store in cool and dry place. It must be in well closed containers. The shelf life will be 2 years.
 
Q6: What's your main payment method?
A: T/T, trade assurance, west union, money gram.
 
Q7: Do you have COA, MSDS, CO, Health certificate, form 9 or other certificate?
A: Yes, we have. pls be free to contact us to get updated one.

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Gold Member Since 2022

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Trading Company
Number of Employees
3
Year of Establishment
2023-04-18