| CAS No.: | 38183-03-8 |
|---|---|
| Formula: | C15h10o4 |
| EINECS: | 253-812-4 |
| Type: | Pharmaceutical Intermediates |
| Appearance: | Powder |
| Quality: | Refined |
| Customization: |
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Audited Supplier Puya Supply 7,8-Dihydroxyflavone CAS 38183-03-8 Treatment Of Alzheimer Disease
Product Name: 7,8-Dihydroxyflavone
Synonyms: 7,8-DIHYDROXYFLAVONE;7,8-dihydroxy-2-phenyl-4-benzopyrone;DIHYDROXYFLAVONE, 7,8-(RG);7,8-Dihydroxyflavone hydrate;7,8-dihydroxy-2-phenyl-1-benzopyran-4-one;8-Dihydroxyflavone;7,8-DIHYDROXYFLAVONE 7,8-DIHYDROXYFLAVONE;7,8-dihydroxy-2-phenyl-4h-1-benzopyran-4-on
CAS: 38183-03-8
MF: C15H10O4
MW: 254.24
EINECS: 253-812-4
Product Categories: Inhibitors;Biochemistry;Di-substituted Flavones;Flavonoids;pharmaceutical;BPC;plant extract
Mol File: 38183-03-8.mol
7,8-Dihydroxyflavone(7,8-DHF) is a naturally occurring flavone found in the tree Godmania aesculifolia. It is a selective tyrosine kinase receptor B(TrkB) agonist that has neurotrophic effects in various neurological diseases such as stroke and Parkinson's disease. 7,8-Dihydroxyflavone binds to the TrkB receptors in a similar way to BDNF, or brain derived neurotrophic factor. When the TrkB receptor is activated, neuroprotective and neurogenetive effects occur in neurons, which tend to affect the dendrites. Dendrites are what reach out from the neurons into the synapse to participate in signaling with other neurons. 7,8-DHF has been shown to promote the growth of these dendrites, and to help restore communication between neurons in animal models.
7,8-Dihydroxyflavone CAS 38183-03-8 of Chemical Properties
Melting point 243-246°C
Boiling point 494.4±45.0 °C(Predicted)
density 1.443±0.06 g/cm3(Predicted)
FEMA 4830 | 7,8-DIHYDROXYFLAVONE
storage temp. Inert atmosphere,Room Temperature
solubility DMSO: soluble24mg/mL
form solid
pka 6.86±0.40(Predicted)
color Yellow or tan
Stability: Stable for 1 year from date of purchase as supplied. Protect from moisture. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 week.
InChIKey COCYGNDCWFKTMF-UHFFFAOYSA-N
CAS DataBase Reference 38183-03-8(CAS DataBase Reference)
Function and Application of 7,8-Dihydroxyflavone CAS 38183-03-8
7,8-Dihydroxyflavone (also known as 7,8-DHF) is a small molecule compound with the chemical formula C15H10O4 and CAS number 38183-03-8. It belongs to the flavone family and is naturally found in plants such as the Tridax procumbens and primrose.
7,8-DHF has been shown to have several potential applications in the fields of medicine and neuroscience due to its ability to modulate certain receptors in the brain. Specifically, it has been found to bind to and activate TrkB receptors, which are involved in the regulation of neuronal survival, differentiation, and plasticity.
Some of the functions and applications of 7,8-DHF are as follows:
1. Neuroprotection: 7,8-DHF has been shown to protect neurons from various types of damage and stress, including oxidative stress, glutamate toxicity, and ischemic injury. This makes it a potential therapeutic agent for neurodegenerative diseases such as Alzheimer's and Parkinson's.
2. Memory enhancement: 7,8-DHF has been found to enhance memory and cognitive function in animal models. This is thought to be due to its ability to stimulate the growth and differentiation of new neurons in the hippocampus, a region of the brain important for learning and memory.
3. Antidepressant effects: 7,8-DHF has been shown to have antidepressant-like effects in animal models, possibly due to its ability to increase the expression of neurotrophic factors such as brain-derived neurotrophic factor (BDNF).
4. Wound healing: 7,8-DHF has been found to promote the healing of skin wounds by stimulating the proliferation and migration of skin cells.
5. Anti-inflammatory effects: 7,8-DHF has been shown to have anti-inflammatory effects by inhibiting the production of pro-inflammatory cytokines.
| Shipping Terms | ||
| By Express | By Air | By Sea |
| Suitable for under 50kg Fast:3-4 days High cost Door to door service Easy to pick up the goods |
Suitable for more than 50kg Fast:3-4 days High cost Airport to airport Professional broker needed |
Suitable for more than 500kg Slow:15-30 days Low cost Port to port Professional broker needed |
Company Profile
Anhui puya biological technology co.,ltd was established in Hefei. Registered capital is 5 million. It is specialized in manufacture plant extract, API and chemicals raw material powder, food additives and oil. which are applied to skin care, healthcare, weight loss products, sex improvement, and pharmaceuticals. We will uphold honesty and pragmatic, innovative and enterprising service purposes, and provide a variety of quality services to our customers at abroad. It aims at supplying good product and comfort service. The strict quality control is to meet the customer's requirement, to get a highly praised and to be high quality supplier. If you have any question, or need samples, please feel free to contact us.
FAQ
Q1. What's the MOQ?
A: Usually 1 kg. It is based on the different product. Some are 1g and some are 1 ton. Please be free to consult our salesman.
Q2. What's the shipping time?
A: If in stock, we will ship it out immediately. By FedEx will be 3~5 days to you.
Q3. If I need less than the MOQ, is it possible?
A: Yes. Please be free to consult our salesman.
Q4. Can you supply the free sample?
A: Usually it is possible. but the shipping cost be paid by customers. It based on the different product. Please be free to consult our salesman.
Q5. How to store the product?
A: Store in cool and dry place. It must be in well closed containers. The shelf life will be 2 years.
Q6: What's your main payment method?
A: T/T, trade assurance, west union, money gram.
Q7: Do you have COA, MSDS, CO, Health certificate, form 9 or other certificate?
A: Yes, we have. pls be free to contact us to get updated one.
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