Puya Supply Rapamycin CAS 53123-88-9 for Anti Cancer

• CAS No.: 53123-88-9
• Formula: C51h79no13
• EINECS: 610-965-5
• Type: Pharmaceutical Intermediates
• Appearance: Powder
• Quality: Refined
• Model NO.: PY202210252201
• Colour: White
• Transport Package: 1kg/Aluminum Bag or 25kg/Drum
• Specification: 99% min
• Trademark: Puya
• Origin: China
• Production Capacity: 5000kilogram/Month

Product Description

Puya Supply Rapamycin CAS 53123-88-9 For Anti Cancer 

Product Name:    Rapamycin
Synonyms:    AY 22989;23,27-EPOXY-3H-PYRIDO(2,1-C)(1,4)OXAAZACYCLOHENTRIACONTINE;NSC-226080;RAPA;RAPAMUNE;RAPAMYCIN;RAPAMYCIN, STREPTOMYCES HYGROSCOPICUS;RPM
CAS:    53123-88-9
MF:    C51H79NO13
MW:    914.17
EINECS:    610-965-5
Product Categories:    VIVACTIL;antibiotic;Chiral Reagents;Heterocycles;Inhibitor;11;Immunosuppressant;All Inhibitors;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Cytokine signaling;Signalling;API;Active Pharmaceutical Ingredients;53123-88-9
Mol File:    53123-88-9.mol

Rapamycin (also known as Sirolimus) is macrocyclic lactone produced by the bacterium Streptomyces hygroscopicus isolated from soil samples from Easter Island. Rapamycin is an antifungal agent with immunosuppressive properties. Rapamycin has antirejection properties without the side effects associated with other antirejection agents. Rapamycin binds to a specific protein, Target of Rapamycin (TOR). TOR is serine/threonine kinase. TOR (mTOR) forms two major complexes: mTORC1,and mTORC2. The mTORC1 consists of mTOR, Raptor, mLST8, FKBP38, PRAS40, and Deptor, and through specific binding of rapamycin to FKBP12, rapamycin inhibits the activity of mTORC1 leading to a decrease in protein synthesis, increased autophagy and inhibition of cell growth.


Rapamycin CAS 53123-88-9 of Chemical Properties
Melting point     183-185°C
Boiling point     799.83°C (rough estimate)
alpha     D25 -58.2° (methan ol)
density     1.0352 (rough estimate)
vapor pressure     0.56 hPa ( 20 °C)
refractive index     1.5280 (estimate)
Fp     87 °C
storage temp.     -20°C
solubility     ethanol: soluble2MM
form     solution
pka    10.40±0.70(Predicted)
color     colorless to yellow
Water Solubility     Soluble in DMSO at 50mg/ml or methan ol at 25mg/mlSoluble in alcohol, dimethyl sulfoxide and dimethyl formamide. Insoluble in water.
Sensitive     Moisture Sensitive/Light Sensitive/Hygroscopic
Merck     14,8114
Stability:    Stable for 2 years? from date of purchase as supplied.? Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.
CAS DataBase Reference    53123-88-9(CAS DataBase Reference)

Function and Application of Rapamycin CAS 53123-88-9 
Rapamycin (CAS 53123-88-9) is a naturally occurring macrolide antibiotic isolated from the bacterium Streptomyces hygroscopicus. It has been found to have a wide range of biological activities and is used in medicine as an immunosuppressant, antifungal, and anticancer agent.

The primary function of rapamycin is to inhibit the activity of a protein called mTOR (mammalian target of rapamycin), which is involved in the regulation of cell growth, proliferation, and survival. By inhibiting mTOR, rapamycin can prevent the growth and division of cancer cells, suppress the immune system, and treat certain autoimmune diseases.

Rapamycin has several applications in medicine, including:

1. Organ transplantation: Rapamycin is used to prevent rejection of transplanted organs by suppressing the immune system.

2. Cancer treatment: Rapamycin has been shown to have anticancer effects and is used in the treatment of various types of cancer, including breast cancer, lung cancer, and renal cell carcinoma.

3. Autoimmune diseases: Rapamycin can suppress the immune system and is used in the treatment of autoimmune diseases such as lupus, rheumatoid arthritis, and multiple sclerosis.

4. Anti-aging: Rapamycin has been found to extend lifespan and improve healthspan in various animal models and is being investigated for its potential as an anti-aging drug.



Packing And Shipping
1.Preferentially DHL, FedEX or TNT for quantity less than 50kg, air shipping for 100kg above, sea shipping for quantity over 500kg.
2.For customers from Russia,Mexico,Turkey,Solvenia,Romania,etc,before placing an order,please kindly confirm if you can make clearance when goods reach your customs.

Shipping Terms
By Express	By Air	By Sea
Suitable for under 50kg Fast:3-4 days High cost Door to door service Easy to pick up the goods	Suitable for more than 50kg Fast:3-4 days High cost Airport to airport Professional broker needed	Suitable for more than 500kg Slow:15-30 days Low cost Port to port Professional broker needed

 

Company Profile
Anhui puya biological technology co.,ltd was established in Hefei. Registered capital is 5 million. It is specialized in manufacture plant extract, API and chemicals raw material powder, food additives and oil. which are applied to skin care, healthcare, weight loss products, sex improvement, and pharmaceuticals. We will uphold honesty and pragmatic, innovative and enterprising service purposes, and provide a variety of quality services to our customers at abroad. It aims at supplying good product and comfort service. The strict quality control is to meet the customer's requirement, to get a highly praised and to be high quality supplier. If you have any question, or need samples, please feel free to contact us.

FAQ
Q1. What's the MOQ?
A: Usually 1 kg.  It is based on the different product. Some are 1g and some are 1 ton. Please be free to consult our salesman.
 
Q2. What's the shipping time?
A: If in stock, we will ship it out immediately.  By FedEx will be 3~5 days to you.
 
Q3. If I need less than the MOQ, is it possible?
A: Yes. Please be free to consult our salesman.
 
Q4. Can you supply the free sample?
A: Usually it is possible. but the shipping cost be paid by customers. It based on the different product. Please be free to consult our salesman.
 
Q5. How to store the product?
A: Store in cool and dry place. It must be in well closed containers. The shelf life will be 2 years.
 
Q6: What's your main payment method?
A: T/T, trade assurance, west union, money gram.
 
Q7: Do you have COA, MSDS, CO, Health certificate, form 9 or other certificate?
A: Yes, we have. pls be free to contact us to get updated one.